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Rectal administration of psilocybin


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#41 hyphaenation

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Posted 14 March 2019 - 08:08 PM

Good info here:   https://mycotopia.ne...shrooms-anally/

 

Check for Golly's anal experiments in there.


Edited by hyphaenation, 14 March 2019 - 08:10 PM.


#42 PistolPete13

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Posted 14 March 2019 - 08:32 PM

I personally would rather eat them raw, than use the back door.

 

But if I was to do this hyph, I would be asking you for a bottle of your freshly squeezed shroom juice..

 

Also thinking about it I can see free-basing psilocin potentially causing problems like sticking to the side of the vessel or to the sides of whatever contraption is used.


Edited by PistolPete13, 14 March 2019 - 09:26 PM.


#43 PistolPete13

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Posted 15 March 2019 - 11:50 AM

 

Psilocybin dose-dependently causes delayed, transient headaches in healthy volunteers

 

Possible mechanisms for these observations are discussed, and include induction of delayed
headache through nitric oxide release. These data suggest that headache is an adverse event to be
expected with the nonmedical use of psilocybin-containing mushrooms as well as the administration
of psilocybin in human research. Headaches were neither severe nor disabling, and should not present a
barrier to future psilocybin research.

Attached File  johnson2012.pdf   622.53KB   7 downloads

 

 



#44 picapau

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Posted 28 March 2019 - 04:36 PM

Fascinating conversation.

I agree with Lego that there may likely be a positive benefit in going through a purge...or several for that matter. Especially if dude is not in the best state of physical/emotional wholeness.

I'm acquainted with peeps who booty bump aya over in Hawaii...but I have never thought to try it. I've not been bothered by the tastes of any of the plants myself.

But I do know that if I don't fast for at least a day before a journey of any type that I risk at least being nauseous, with mushshrooms and outright purging with aya.

The bit about the vagus nerve is important IMO. I actually think puking helps in a reset way around this connection.

The bit where McKenna talked about tryptamine molecules binding easily with melanin and seratonin receptors was definitely expressed in the book, "True Hallucinations" (i don't know about elsewhere).....it was Dennis that made this claim. He suggested that because all 3 of the molecules have similar outer electron shell structure that they binded easily and in a way that made them super conductive. Like when playing a harmonic note on a guitar string. The result was an activation of the neo-cortex f the brain which resulted in heightened sensory qualities and ultimately the suggestion that tryptamine induced hallucinations are not actually hallucinations at all but rather what is actually present in reality when our senses are able to compute them.
It was never stated in the book where Dennis gathered this knowledge....and I want to suggest that he was getting directly from the mushrooms, as he went pretty far 'out there' if I remember correctly. It's been a lot of years since I read that book.


The clinical studies that pointed toward %s of peeps getting nausea may not account for the wholeness of their inner landscape...or maybe some people just can't stomach the experience, quite literally.

But my gut says to puke and puke hard...get well as they say.

Edited by picapau, 28 March 2019 - 04:37 PM.

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#45 DonShadow

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Posted 09 April 2019 - 09:47 PM

Through persisting on this path of inquiry with my friend, I have learned a lot of things that I certainly didn't expect. My understanding of the meaning of relationship has progressed in great strides. I am able to perceive a kind of unseen dimensionality at work in my interactions with other people that I didn't see before. The intentions that we apply toward a rational understanding of a problem so often fall short of the mark, and yet, in our persistence, unexpected solutions can reveal themselves quite plainly. Now, this might sound strange to some, but it has become increasingly clear to me that the self I perceive is in fact only the sensory organ of a larger organism which is operating semi-autonomously throughout the collective. Through eating mushrooms and opening up my psyche to this higher mode of logic, it seems possible to understand, or at least be shepherded by the motivations of the unconscious on the transpersonal level. My myopic rational approach to my friend's nausea was only a necessary blunder that allowed me to see the folly of my ego, which was in desperation merely miming the qualities that I dislike most in my father, who used to attempt to treat every ailment as a dietary problem, or a symptom of insufficient exercise. In recognizing this, I not only found that I was able to make clearer sense of my friend's needs, desires and abilities, but I also located an in-road to uprooting the redundancies of my father's powerful residual influence on my psyche. I am inclined to say that I owe this realization to the commitment to eat mushrooms with my friend, rather than as a sober bystander. This method seems to open up more effectively to mutual learning, which I believe is a much more equanimous and realistic goal, for one with so little experience as I.

 

On another note, my friend has responded very well to vaporized DMT extracted from mimosa root bark, so he has something that works consistently for him. His first attempt with this extraction (40mg vaporized) resulted in a deep opening experience with little bodily discomfort. I will likely still attempt a rectal administration with an acid/base solution, but that can wait for now.


Edited by DonShadow, 09 April 2019 - 09:49 PM.

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#46 picapau

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Posted 09 April 2019 - 09:51 PM

 

 

 The intentions that we apply toward a rational understanding of a problem so often fall short of the mark, and yet, in our persistence, unexpected solutions can reveal themselves quite plainly. Now, this might sound strange to some, but it has become increasingly clear to me that the self I perceive is in fact only the sensory organ of a larger organism which is operating semi-autonomously throughout the collective.

that was fucking cool to read

 

 

and a great post.

 

glad your friend found a way to open those gates~






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