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Mixing psilocybin with lexapro


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#21 Thirdeyeplants

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Posted 06 July 2019 - 06:32 PM

There are also studies showing that saint johns wort does not mix well with SSRIs...
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#22 Cuboid

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Posted 07 July 2019 - 03:04 AM

There are also studies showing that saint johns wort does not mix well with SSRIs...

Indeed, it seems to have similar action as SSRI's so it is sensible to treat is as if it were an SSRI in terms of what you do and don't mix it with.


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#23 Opendoors

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Posted 16 July 2019 - 02:26 PM

Does anybody have a recommendation on how long one would have to stop taking SSRI's before they start microdosing?

#24 Oneyedraven

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Posted 16 July 2019 - 03:19 PM

Step down protocol is normally 2 weeks. I gave it 30 days just to be sure. I worked with my dr under the “assumption” of wanting to go off of the SSRIs and had an emergency plan (starter kit doses) of Ssri and a script for a few (5) benzodiazepines just in case I crashed and burned on the wean off. I did start myself on l-tryptophan (serotonin precursor) and GABA - slows down the fight or flight response. To help bring my brain chemistry back to baseline. I also had very positive results from micro-dosing, .2mg dry 5 on 2 off.
Had a few failed grows and am out , so far so good! I do not regret going off the anti depressants- but it’s not for everybody.
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#25 Oneyedraven

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Posted 16 July 2019 - 03:19 PM

Step down protocol is normally 2 weeks. I gave it 30 days just to be sure. I worked with my dr under the “assumption” of wanting to go off of the SSRIs and had an emergency plan (starter kit doses) of Ssri and a script for a few (5) benzodiazepines just in case I crashed and burned on the wean off. I did start myself on l-tryptophan (serotonin precursor) and GABA - slows down the fight or flight response. To help bring my brain chemistry back to baseline. I also had very positive results from micro-dosing, .2mg dry 5 on 2 off.
Had a few failed grows and am out , so far so good! I do not regret going off the anti depressants- but it’s not for everybody.
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#26 Thirdeyeplants

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Posted 17 July 2019 - 01:24 AM

I used a 30 day stepdown plan for my SSRI s and benzodiazepines. I was on very high doses, and even doing it gradually, I know for a fact I was not pleasant to be around. Now, that is the stepdown. I have not found any concrete numbers, but a lot of anecdotal suggestions that you wait 3 weeks after the meds are out of your system, however each and every one of us has a unique biochemical make-up and may take varying times to "baseline". I too have found GABA to be very helpful with the anxiety and L-lysine as a seratonin precursor. As im sure you are aware, lions mane has been proven high in brain growth factor and helps with neurogenesis. I have seen promising evidence to show that this helps the growth of new brain cells and "communication infrastructure" and can personally attest to a boost in mood and mental clarity, and has been very helpful in "getting back to baseline"...
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#27 deepblueseawhale

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Posted 17 July 2019 - 03:17 AM

Does anybody have a recommendation on how long one would have to stop taking SSRI's before they start microdosing?

 

Depends on the type of the SSRI and it's half life. 30 days to be on the safe side. See Harvard's page Going off antidepressants - https://www.health.h...antidepressants.

 

As for alternatives St. John's Wort works great if you can get your hand on a quality alcohol extract (preferably tincture). You might even make one yourself if you live in a region where it grows as its full bloom now. There's a great forum SJW info with great advice from various users who used it for years.

 

You may also check out amino acid L-tryptophan, which naturally increases the level of serotonin by providing essential building blocks to the brain.

 

As for combination with fungi, SJW can potentiate its effects while L-tryptophan will dull them. To be on the safe side she can stop using them about a week or so before the journey and continue in the days afterwards. Also she should not take both together (SJW+L-tryptophan) as that might be dangerous. So one or the other.


Edited by deepblueseawhale, 17 July 2019 - 03:19 AM.

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#28 Alder Logs

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Posted 17 July 2019 - 12:57 PM

When I made tincture of St.John's wort, if memory serves, I used a one to one dilution of everclear and submerged the flowers in it.  I just visited a friend the other day and saw his property was covered in it in full bloom.  So, maybe I should make some this year, because it's there.  I just found this site that has the instructions for making the tincture, which looks like what I did: http://www.susanhutc.../st-johns-wort/.  It's really cool how the green buds and yellow flowers make that deep red tincture. 


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#29 Opendoors

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Posted 17 July 2019 - 01:04 PM

When I made tincture of St.John's wort, if memory serves, I used a one to one dilution of everclear and submerged the flowers in it. I just visited a friend the other day and saw his property was covered in it in full bloom. So, maybe I should make some this year, because it's there. I just found this site that has the instructions for making the tincture, which looks like what I did: http://www.susanhutc.../st-johns-wort/. It's really cool how the green buds and yellow flowers make that deep red tincture.


That's awesome...I got to try that for sure

#30 Alder Logs

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Posted 17 July 2019 - 01:14 PM

Just for fun; how is the word, "work," pronounced?  That is how the word, "wort," is also pronounced.  Just as in hospitals, people are put in, "wards," not, "words," it's not St.John's wart.  You don't make beer from a wart, either.  St. John may have had a wart, it's possible.  But, we won't be making medicine from it.



#31 Juthro

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Posted 17 July 2019 - 01:29 PM

  You don't make beer from a wart, either.  

 

I've seen plenty of strange things included in the wort, but thank the heavens, never a wart.... 

The very thought makes me a little squeamish, lol.


Edited by Juthro, 17 July 2019 - 01:29 PM.


#32 Opendoors

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Posted 17 July 2019 - 01:46 PM

Hmmm... isnt a wart some type of fungus?lol

#33 deepblueseawhale

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Posted 18 July 2019 - 05:48 AM

When I made tincture of St.John's wort, if memory serves, I used a one to one dilution of everclear and submerged the flowers in it.  I just visited a friend the other day and saw his property was covered in it in full bloom.  So, maybe I should make some this year, because it's there.  I just found this site that has the instructions for making the tincture, which looks like what I did: http://www.susanhutc.../st-johns-wort/.  It's really cool how the green buds and yellow flowers make that deep red tincture. 

 

Yes, that's the way I do it as well - 1:1 ratio, everclear and flowers with a bit of leaves. I too just love that deep, thick red color it gets once the tincture is ready. It's just like blood :)

Also I found it's great if you combine it with Wild Oats Milky Seed tincture (Gaia Herbs make some great one). It takes the edge off SJW tincture that some people might experience as a bit pushy/manic. It also provides "moist", calming and rejuvenating energy for people who are a bit on the dry end of their constitution.



#34 MsBehavin420

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Posted 03 August 2019 - 07:32 AM

Hey so this hits me personally. I'm very happy to share my experience together with many others whom have experienced what happens when shrooms are mixed with an SSRI. First off very glad that seratonin syndrom has been discussed, I often forget about it myself and got a re up on the knowledge. So.
My girlfriend is on an SSRI also. Depression is tough and I think that SSRI is fine, but its not the medicine that cured my depression. Shrooms were. So naturally I want my girlfriend to enjoy and be healed from shrooms, but I've noticed that she trips much much less. The effects are alway much less for her, however the medicine and spirit is able to get through. Every shrooms trip I have I ask the medicine to help her and she has shown interest into cultivating that medicine for herself. And I am so greatful that the spirit comes through to her when we trip.

Through this, I am hoping that she learns a lifelong skill, and is able recover from depression. That is all we can do, to put options out there, but ultimately we must let them decide for themselves. In the end if she doesn't have or believe in the same medicine that wee do then I must let her find the path towrads it and aid her, instead of giving her fishes.

In terms of tripping, I think that bad trips are just trips that we have to have to experience to reach better trips in the future. It is possible that bad trips make her rethink about tripping. Trips often make people rethink what they thought tripping was, and it is an intense experience.

All those whom have shared their experience should be able to be good resources for the future.

maybe she should take a smaller does (micro) bc what you're explaining... less effect in the visual department and more of the medicinal quality, is possible that it's bc its working As a med Not as a "get high" drug.
Similarly to how marijuana, when being used as a pain management will have a lesser effect on the mind bc the use is specifically intended for the pain issue. Make any sense?
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#35 MsBehavin420

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Posted 03 August 2019 - 07:38 AM

Seeking info on fungi and anxiety for my daughter. I want to exhaust all natural options before she goes and gets chemicals from a doctor.
she says it feels heavy in her chest.

I know of M. A. P. S for psychedelic therapy. I'm sure we are headed into a excellent time for natural discovery since Oakland is a free place now.

Also, gawrsh... Who'd have thunk we would be seeing the end of prohibition happen, right before our very eyes? So amazing the forward motion.

#36 Pakil

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Posted 02 September 2019 - 03:28 PM

This exact scenario is what brought me here to mycotopia. I got really scared when the "medicine" that always helped me find a reset button was no longer responding. Well, that and the crippling depression and anxiety. There is extensive research that pointed me in the direction of the 5HTP receptors and related health supplements. I have found great resolve and clarity in the "treatments" I have chosen, but for me the first step was to get away from the SSRI. (That was my choice and the correct one for me. I understand this is not the case for everyone) you are in the right place, as I found a good majority of my early information right here...

 
I did the same thing. I was like, "Why don't I try the medicine that I grow? Duh". I talked to my physician and my therapist and went off all of the meds (xanex, prozak and kpins) under their supervision. I've been microdosing ever since.
 
I've had three friends/clients tell me that microdosing took away their suicidal tendencies.

I apologize for hijacking your thread. Catsandbats, what did you tell your doctor and therapist. Mine are both adamant that I need meds, and I’m a bit afraid to tell them *why* I want to do this. I’ve suffered from depression and suicidal thoughts since I was 15. :( (even while medicated)

#37 RainbowCatepillar

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Posted 02 September 2019 - 04:19 PM

I just want to share that this thread is so helpful!
My girlfriend just recently got off cymbalta (HORRIBLE shit) 

and has struggled with withdrawals for the last month. Please, if 

you decide to go the big pharma route, look into the potential side effects.

To my surprise, I've found that the side effects of cymbalta are so bad, people 

have literally lost their jobs and had their lives ruined as a result of it. It's one of the

most physically addictive drugs you can possibly get on.. And many psychiatrists aren't aware

of this when they recommend it.

Just want to remind anyone reading this to look into

the drugs before getting on them or there may be 

hell to pay.

 

Again, thank you for this thread. 

We'll see if a microdosing regimen works.


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#38 Moonless

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Posted 02 September 2019 - 08:24 PM

 

Hey so this hits me personally. I'm very happy to share my experience together with many others whom have experienced what happens when shrooms are mixed with an SSRI. First off very glad that seratonin syndrom has been discussed, I often forget about it myself and got a re up on the knowledge. So.
My girlfriend is on an SSRI also. Depression is tough and I think that SSRI is fine, but its not the medicine that cured my depression. Shrooms were. So naturally I want my girlfriend to enjoy and be healed from shrooms, but I've noticed that she trips much much less. The effects are alway much less for her, however the medicine and spirit is able to get through. Every shrooms trip I have I ask the medicine to help her and she has shown interest into cultivating that medicine for herself. And I am so greatful that the spirit comes through to her when we trip.

Through this, I am hoping that she learns a lifelong skill, and is able recover from depression. That is all we can do, to put options out there, but ultimately we must let them decide for themselves. In the end if she doesn't have or believe in the same medicine that wee do then I must let her find the path towrads it and aid her, instead of giving her fishes.

In terms of tripping, I think that bad trips are just trips that we have to have to experience to reach better trips in the future. It is possible that bad trips make her rethink about tripping. Trips often make people rethink what they thought tripping was, and it is an intense experience.

All those whom have shared their experience should be able to be good resources for the future.

maybe she should take a smaller does (micro) bc what you're explaining... less effect in the visual department and more of the medicinal quality, is possible that it's bc its working As a med Not as a "get high" drug.
Similarly to how marijuana, when being used as a pain management will have a lesser effect on the mind bc the use is specifically intended for the pain issue. Make any sense?

 

I'm proud to say that she has been doing Micro dose for a full week. The last doctor she went to recomended a smaller SSRI dose and that was 20 days age.



#39 RainbowCatepillar

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Posted 03 September 2019 - 01:48 AM

 

 

Hey so this hits me personally. I'm very happy to share my experience together with many others whom have experienced what happens when shrooms are mixed with an SSRI. First off very glad that seratonin syndrom has been discussed, I often forget about it myself and got a re up on the knowledge. So.
My girlfriend is on an SSRI also. Depression is tough and I think that SSRI is fine, but its not the medicine that cured my depression. Shrooms were. So naturally I want my girlfriend to enjoy and be healed from shrooms, but I've noticed that she trips much much less. The effects are alway much less for her, however the medicine and spirit is able to get through. Every shrooms trip I have I ask the medicine to help her and she has shown interest into cultivating that medicine for herself. And I am so greatful that the spirit comes through to her when we trip.

Through this, I am hoping that she learns a lifelong skill, and is able recover from depression. That is all we can do, to put options out there, but ultimately we must let them decide for themselves. In the end if she doesn't have or believe in the same medicine that wee do then I must let her find the path towrads it and aid her, instead of giving her fishes.

In terms of tripping, I think that bad trips are just trips that we have to have to experience to reach better trips in the future. It is possible that bad trips make her rethink about tripping. Trips often make people rethink what they thought tripping was, and it is an intense experience.

All those whom have shared their experience should be able to be good resources for the future.

maybe she should take a smaller does (micro) bc what you're explaining... less effect in the visual department and more of the medicinal quality, is possible that it's bc its working As a med Not as a "get high" drug.
Similarly to how marijuana, when being used as a pain management will have a lesser effect on the mind bc the use is specifically intended for the pain issue. Make any sense?

 

I'm proud to say that she has been doing Micro dose for a full week. The last doctor she went to recomended a smaller SSRI dose and that was 20 days age.

 

Awesomeeee! How has the microdoses been treating her? Any noticeable changes or anything in her thought patterns or behaviors?


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#40 Pakil

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Posted 03 September 2019 - 10:11 AM

I’m still hoping someone can help me with my post #36 up there, I’m really excited about the possibilities without this shit! :)




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