2171 replies to this topic

[riseabovethought]

Yea, I was just laughing about that one too!  It sure gives it a whole different perspective real quick.  Must not be that bad, really.  

Edited by riseabovethought, 13 May 2022 - 10:55 AM.

[bezevo]

i am eligible for third shot . what are opinions on ether if  it's  worth it or how beneficial is the 3rd booster possibly is ?

 

BEZ

[shiftingshadows]

one concern is:

not aspirating injections

https://duckduckgo.com/?q=aspirating+injections&t=h_&ia=web

https://duckduckgo.com/?q=aspirating+injections%2C+dr.+John+Campbell&t=h_&ia=web

other considerations may be addressed here:

https://www.youtube.com/user/Campbellteaching/videos

 

 

I did get a third, but am not presently interested in a 4th.

 

Seems everyones' vulnerabilities and health varies, and that statistics, often do not match expected outcomes, ie. it's all sort of a 'crap shoot'.

 

Anyway I still mask when shopping.

Edited by shiftingshadows, 07 May 2022 - 01:17 PM.

[riseabovethought]

Obviously, after getting vaccinated, there are still a few other things one could do, such as consume things that help protect us.  Here's a study wondering if mushrooms are relevant to the pandemic.

 

Early Trials Underway to Test Mushrooms as COVID Treatment

By Marcia Frellick

 

 

Nov. 9, 2021 -- Early trials are under way to test medicinal mushrooms and Chinese herbs to treat COVID-19 patients with mild to moderate symptoms.

 

The first two phase 1 randomized, double-blind, placebo-controlled trials have begun at UCLA and the University of California San Diego to treat COVID-19 patients who were quarantining at home with mild to moderate symptoms. A third trial is investigating the use of medicinal mushrooms given after COVID-19 vaccines.

 

The researchers have also launched a fourth trial testing the mushrooms against a COVID booster shot alone. It looks at the effect in people who have underlying conditions that would reduce their vaccine response. An article in JAMA last week described the trials.

 

The two mushroom varieties being tested — turkey tail and agarikon — are available as over-the-counter supplements, according to the report. They are a separate class from hallucinogenic or "magic" mushrooms being tested for other uses in medicine.

 

"They are not even as psychoactive as a cup of tea," Gordon Saxe, MD, PhD, MPH, principal investigator for the trials, says.

 

For each trial, researchers plan to recruit 66 people who are quarantined at home with mild to moderate COVID-19 symptoms. Participants will be randomly assigned either to receive the mushroom combination, the

Chinese herbs, or a placebo for 2 weeks, according to the JAMA paper.

 

D. Craig Hopp, PhD, deputy director of the Division of Extramural Research at the National Center for Complementary and Integrative Health, told JAMA in an interview that he was "mildly concerned" about using mushrooms to treat people with active coronavirus infection.

 

"We know that a cytokine storm poses the greatest risk of COVID mortality, not the virus itself," Hopp said. "The danger is that an immune-stimulating agent like mushrooms might supercharge an individual's immune response, leading to a cytokine storm."

 

Stephen Wilson, PhD, an immunologist who consulted on the trials when he was chief operating officer of the La Jolla Institute for Immunology, says in the JAMA article that a cytokine storm is unlikely for these patients because the mushroom components "don't mimic inflammatory cytokines." Wilson is now chief innovations officer at Statera Biopharma.

 

"We think the mushrooms increase the number of immunologic opportunities to better see and respond to a specific threat. In the doses used, the mushrooms perturb the immune system in a good way but fall far short of driving hyper or sustained inflammation," Wilson said.

 

Saxe said the FDA process was extensive and rigorous and FDA investigators also asked about potential cytokine storms before approving the trials.

 

Cytokine storm is not an issue with a healthy response, Saxe pointed out. It's a response that's not balanced or modulated.

"Not a Crazy Concept"

 

Saxe pointed out that one of the mushrooms in the combo they use — agarikon — was used to treat pulmonary infections 2,300 years ago.

"Hippocrates, the father of western medicine, used mushrooms," he said.

 

"Penicillin comes from fungi. It's not a crazy concept. Most people who oppose this or are skeptics — to some extent, it's a lack of information."

Saxe explained that there are receptors on human cells that bind specific mushroom components.

 

"There's a hand-in-glove fit there," Saxe said, and that's one way mushrooms can regulate immune cell behavior, which could have an effect against the coronavirus.

 

Daniel Kuritzkes, MD, chief of the Division of Infectious Diseases at Brigham and Women's Hospital in Boston, , who was not part of the study, says he wasn't surprised the FDA approved moving forward with the trials.

 

"As long as you can demonstrate that there is a rationale for doing the trial and that you have some safety data or a plan to collect safety data, they are fairly liberal about doing early-phase studies. It would be a much different issue, I think, if they were proposing to do a study for actual licensing or approval of a drug," Kuritzkes says.

 

As yet unanswered, he noted, is which component of the mushrooms or herbs is having the effect. It will be a challenge, he said, to know from one batch of the compound to the next that you have the same amount of material and that it's going to have the same potency among lots.

 

Another challenge is how the mushrooms and herbs might interact with other therapies, Kuritzkes said.

 

He gave the example of St. John's Wort, which has been problematic in HIV treatment.

 

"If someone is on certain HIV medicines and they also are taking St. John's Wort, they basically are causing the liver to eat up the HIV drug and they don't get adequate levels of the drug," he said.

 

Though there are many challenges ahead, Kuritzkes acknowledged, but added that "this is a great starting point."

 

He, too, pointed out that many traditional medicines were discovered from plants.

 

"The most famous of these is quinine, which came from cinchona bark that was used to treat malaria." Kuritzkes said. Digitalis, often used to treat heart failure, comes from the fox glove plant, he added.

 

He said it's important to remember that "people shouldn't be seeking experimental therapies in place of proven therapies, they should be thinking of them in addition to proven therapies."

https://www.webmd.com/lung/news/20211109/testing-mushrooms-as-covid-treatment

Edited by riseabovethought, 21 May 2022 - 11:27 AM.

[shiftingshadows]

"Hope springs eternal (in the human breast)."

[Juthro]

"Hope springs eternal (in the human breast)."

 

I tried to look for some hope one time, but she slapped me.

 

(sorry, couldn't help myself)

[shiftingshadows]

https://duckduckgo.c...7e69e63de2a.jpg

[riseabovethought]

More relevance
Doctors Will Be Given 'Magic' Mushrooms for Pandemic Burnout: Study (insider.com)

 

Essential healthcare workers utilizing mushrooms for stress management from Pandemic.
https://www.miamiher...e256623961.html

Edited by riseabovethought, 25 May 2022 - 01:06 PM.

[Myc]

Still on topic (I think). I watched this series on n-flix recently and I highly recommend giving it a review:

[Direct Link]

 

The video goes a long way to explain the seeming disconnect between big government and The People. It also avoids being overly biased. I found the video to be quite even-handed.

Added bonus:

There is also a suggested path by which we (The People) can begin to effect more change in leadership and legislation. Start at the local level by participating in municipal, county, and state government.

 

 

[rockyfungus]

[Direct Link]

[TVCasualty]

Here's a handy resource for following the still-ongoing pandemic: https://charts.medriva.com/us

 

 

Screen shot of map of current week-to-week trend in new confirmed cases:

 

There is a lot of constantly-updated info in that link.

 

 

In other news, I really hope "monkeypox" doesn't go viral, so to speak, since the fucked up COVID response has primed a lot of people to completely ignore the next outbreak of anything even if the fatality rate is considerably higher, though at least it will be very hard for most diseases to match the extreme contagiousness of recent COVID variants.

 

 

[shiftingshadows]

....

 

 

In other news, I really hope "monkeypox" doesn't go viral, so to speak, since the fucked up COVID response has primed a lot of people to completely ignore the next outbreak of anything even if the fatality rate is considerably higher, though at least it will be very hard for most diseases to match the extreme contagiousness of recent COVID variants.

May 31, 2022 update  ... unbelievable .... more lies out of China

 

as if Global "Warming" & Putin's reckless war wasn't enough ...

 

"NIH, Wuhan were working on monkeypox"

 

[Direct Link]

Edited by shiftingshadows, 01 June 2022 - 03:08 PM.