I wonder if you can check two assumptions of mine regarding microdosing shrooms.
I am taking two meds for managing remnants of severe depression.
- Wellbutrin (generic is Bupropion, atypical antidepressant, 400mg/d)
- Pamelor (generic is Nortriptyline, tricyclic antidepressant, 125mg/d)
From my research, microdosing has a decent chance of helping my mood swings, which are managable, but still disruptive. That's why I am on Mycotopia, rather than for macrodosing for learning and self healing, although those really interest me too.
I microdosed 0.2g dried Golden Teacher for a month, 1 day on, 2 days off (Fadiman protocol). I think I saw results, my wife swears she did too. There were never any perceptible effects, like brighter colors, hallucinations, "overt" brightening of mood. Considering the lack of effects, I wondered if I was taking the right dose, so, I took 0.5-0.6g a few times, with no effects either.
So, my first assumption is that my meds are blocking any tripping, or any overt effects. From what I read, it is probably the Pamelor, since Welbutrin does not interact with serotonin receptors, and Pamelor, while not a SSRI or SNRI, has some interactions with serotonin receptors. I wonder if this sounds reasonable to Mycotopia. I mean, I think I should have felt something at 0.6g, right?
In light of this, I began researching if antidepressants block any and all effects of microdosing. I didn't find much info in the OMC regarding this. My second assumption is that despite no overt effects, I would probably still see benefit from microdosing at a reasonable level, like 0.2g, following some protocol, such as Fadiman's or Stamets'. I wonder if Mycotopia would agree with the concept, or, if you guys have seen this, and microdosing is not going to provide benefits at all. I mean, I think there is more to shrooms than just just binding with serotonin receptors, but, I am not really sure,
Thank you for the help.