Intriguing and harrowing case report of someone who injected themselves with mushroom (P. cubensis) tea...spores included. He nearly killed himself doing this, and was on ICU life support for multiple-system organ failure for some time. He had bipolar disorder type I and had been researching ways to treat his opioid dependence and depression, and was intrigued to give psychedelics a try.
One very weird take away from this: "...the species of mushroom he had injected was now growing in his blood". Not only did the mushroom spores survive boiling, but they germinated and started growing in his bloodstream according to this.
Curious about the wider evolutionary implications of this pertaining to the mushroom...given how tough and resilient mushroom spores appear to be, it calls into question the hypothesis put forward that psilocybin acts as a repellent...perhaps it more likely acts as an attractant. Makes me curious about the association of P. cubensis with bovine dung, perhaps bovines are ingesting spores and helping distribute them...I wouldn't put it past those crafty fungi.
Giancola et al. (2021) A “trip” to the ICU: intravenous injection of psilocybin. Journal of the Academy of Consultation-Liaison Psychiatry, In Press.