I'll chime in here with my 2 cents as well.
1) For the HPBCD DMT experiments, prefer using "clean DMT" or DMT that has been cleaned using a sodium carbonate wash, procedure below:
2) PKA of DMT is 8.75 or so, so please do not use a sodium bicarbonate wash -- it will eat up most of your DMT, as ph of bicarb is not high enough, it needs to be 1 to 2 points higher than PKA of DMT, at 11 or 11.5 or so is perfect, where 100% sodium carbonate PH is at, found in pool isle of home box store.
3) As performing a "sodium carbonate wash" on crystals AFTER they are freeze precipitated is a pain in the ass, will attempt to perform a sodium carbonate wash in real time this time, immediately on the 1st pull, and every pull thereafter.
4) For example, a procedure which yields 1.5g DMT from 150 gram powdered bark: the first pull is using 75ml naptha on 150g powdered bark mixed into 1.7 liter lye water (1.5 x 150g bark = use 225g lye dissolved into the 1.7 liter 150 degree hot water by slowly sprinkling in lye using safety goggles and long chemical resistant gloves that go up each arm, and standing back as far as possible...the hot water will fizz but not boil up) in a 2 Liter erlenmeyer flask (.5 x 150g bark = use 75ml naptha pull for each of the 4 pulls). An erlenmeyer flask makes it easy to do pulls using a long glass pipette, as the top of flask is tapered, so all the naptha collects at the top for easy pull.
Use an electronic thermometer to check the temp of the Lye water bark mix, when the lye water cools down from 150 degree F to around 115 to 110 degree F, then it's time to add your 75ml of naptha, make sure your 2L flask is sitting on a mitten or similar...this makes it easy to swirl your flask to mix the contents, make sure you are using the proper rubber stopper number to seal the top of your flask once you turn it upside down then right side up to mix the contents as well.
Prefer to do a combination of swirling and a couple of upside down then right side up turns of the 2L flask, then once right side up, let the rubber stopper out, and let the stopper just barely sit in the flask (not tight), so gasses can exit. After 1/2 hour, all the 75ml of naptha will migrate & collect at the top of the tapered erlenmeyer flask...use your long glass pipette to collect the naptha, that's it! very easy, no mess, and the tapered erlenmeyer flask and glass pipette with round rubber plunger at the end makes it easy to collect the naptha at the top without collecting any lye water by accident. This is the way a chemist can do it.
to clean...then use 1/4 of the amount of each naptha pull or (0.25 x 75ml pull = use 19ml of warm water at 100 degree F with a dash of sodium carbonate dissolved into it) till ph = 11 to 11.5 of the wash water.
5) So then add the 75ml saturated naptha bark pull into a sep funnel, add 19ml of warm (100 degree F) sodium carbonate solution, and shake & swirl it all together in the sep funnel for 5 seconds, then separate off the bottom layer which will be the sodium carbonate water and dispose of it, and let out the top layer of sodium carbonate washed clean naptha into a 1/2 pint jar, put lid on jar, place in freezer, and freeze precipitate overnight, and collect clean crystals in morning by pouring over a coffee filter attached to a 1/2 pint wide jar with rubber band.
6) Will be using this new batch of real time "sodium carbonate wash cleaned naptha pull" DMT to do a series of HPBCD experiments later this week, will then report back, will be complexing 40mg of DMT to 280mg of HPBCD powder to form a sticky glob, will place under tongue for 15 minutes and take 250mg of tetrahydroharmine 1 hour earlier, and report back.
1) place 40mg of DMT onto a spoon
2) add 1:1 molar ratio of host drug to HPBCD powder, this means 1:7 mg ratio DMT to HPBCD
3) this means 40mg dmt placed on spoon, then add 280mg of HPBCD on top DMT
4) add many drops of water to the mix
5) Knead or crush the HPBCD powder into the dmt using the end of a spoon then stir it all for 30 seconds using a toothpick
6) place sticky glob (HPBCD powder forms sticky complexes) under tongue for 15 minutes
7) the "sticky glob" can be left out and the water will evaporate to leave a solid complex which can be placed under tongue too, but I never do this, I just directly place the sticky glob under tongue right away, 30 second procedure, works extremely well, same way weightlifters used to form HPBCD complexed pro-hormones back in the day before they were banned, for sublingual "under tongue" use.
HPBCD DMT very bioavailable sublingually under tongue, combo with tetrahydroharmine, Ayahuasca - Pharmahuasca - Welcome to the DMT-Nexus
Edited by tregar, 10 May 2021 - 11:56 AM.