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HPBCD DMT sublingually active under tongue


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#1 tregar

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Posted 01 January 2022 - 11:02 AM

2 minute formed HPBCD DMT liquid very bioavailable sublingually under tongue & outperforms DMT salts orally by many factors in personal trials, combo with tetrahydroharmine, Ayahuasca.
 
Part 0: 12 reasons pure THH or tetrahydroharmine rocks (this post #1 in middle)
Part 1: HPBCD complexed DMT experimental dosage, effects & duration, over 44 sublingual DMT experiences over a year's time (this post #1 at bottom). Many times stronger than oral DMT. Updated 1-1-2022.
Part 2: Receptorome chart & explanation 
Part 3: Tetrahydroharmine (THH) effects 
Part 4: Tetrahydroharmine receptorome similarities to mescaline; potentiates cactus & safety note 
Part 5: Chemist Patrick Arnold's HPBCD prohormones & bloodwork studies 
part 6: Dr. Narang: "with sublingual" or "under the tongue" better than buccal, gingival & palatal, absorption of drugs through the sublingual route is 3 to 10 times greater than oral route and is surpassed by hypodermic injection.
part 7: a little bit on my 70 Ayahuasca experiences, doses & visions 
part 8: New research: Morning glory contains 5 stimulating LSD-like drugs, soluble only in wine/alcohol, only sparingly soluble in water 
part 9: 20 minute visionary visit from a dead Aztec Shaman
part 10: One way to make pure tetrahydroharmine 
part 11: From the archives of DMT world: How to easily extract 2.3g DMT from 170g bark using a 2 liter Erlenmeyer flask 
part 12: Out of print writings on the Divine Plant of the Incas, coca leaf visions...and writings on strong euphoria from coca leaf tea bags soaked in wine, forming orally active cocaethylene in the liver, discovered in 1994. Explains the popularity of Vin Mariani (coca leaf soaked wine) with both popes, Thomas Edison and countless celebrities.
part 13: THH + mushrooms report from JKW.
 
part 14: Multiple encounters with death & depression.
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10.18.2021 update:
 
Tetrahydroharmine + 1-acetaldehyde LSD (similar to ALD-52) combo, like high dose mescaline:
 
In closing, I'm going to post what I believe to be a revolutionary psychedelic combination, and it's dirt cheap compared to the rare and very expensive cactus...but it's just as long-lasting, profound, highly euphoric, visual, neon-colorful, music-enhancing & super deep head space, with zero-anxiety as two feet of fat bridgesii.
 
300mg THH + 250ug 1-acetaldehyde LSD report (2oz fresh cold sherry wine morning glory extract can substitute as well)
 
1) The combo of 300mg THH + 1-acetaldehyde LSD makes the beauty & aesthetic enhancement way stronger than LSD alone. Same "over the top" beauty enhancement as high dose cactus tea.
 
2) The music sounds much better than LSD alone, it feels very much like when you combine mescaline with LSD, as THH is like the beta-carboline version of mescaline.
 
3) The combo is highly visual & neon-colorful with open eyes, with each of the 12 trips spaced two weeks apart experienced so far have seen neon-red-greens, neon-orange-blues, and even neon-purple-yellows, supercolorful just like high-dose cactus tea.
 
3) Very beautiful combination.
 
4) This 300mg THH + 250ug 1-acetaldehyde LSD combo is one of my absolute favorites, have since used it every 2 weeks x 12 times now. No re-doses necessary as the THH has a 10.5 hour half life with peak at 5.25 hours. Very powerful: Lasts all evening, infinitely beautiful. I've consistently reached +5 Shulgin level strength every time, very life changing experience every time. Super deep head space, Divine to the extreme, heavenly mescaline-like spiritual euphoria for hours on end, no words to describe.
 
Note: THH is NOT an MAOI, she (feminine spirit) is a psychedelic SRI or serotonin reuptake inhibitor just like the following psychedelic serotonin reuptake inhibitors: mescaline, LSD, shrooms, ibogaine.
 
Make sure your THH is pure and not contaminated with unconverted harmaline (which is a RIMA/maoi). Dab some THH on a wet cue tip, rub on paper plate, hold under blacklight, if it glows blue you have THH, if any green glow, you have harmaline in it, keep in mind harmine also glows blue too though.
 
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(0) Part 0: 12 reasons pure THH or tetrahydroharmine rocks
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1. Part 10 of this paper: shows how to convert harmaline to pure THH in 1.5 hour for the first time (very fast) with 75% yield. TIHKAL THH entry also achieved 75% yield. Post also shows how to check the blue glow under blacklight to make sure it is pure. Any green in the glow means you still have un-converted harmaline, but follow instructions and you won't have any unconverted.
 
1. Dennis Mckenna Ph.D: page 115:
Thus, tetrahydroharmine may prolong the half-life of DMT by blocking it's intraneuronal uptake, and hence, its inactivation by MAO, localized in mitochondria within the neuron.
 
In my experience, THH doubles the half-life of DMT, so when used sublingually or orally, you get a full strong 90 minutes out of it with long afterglow.
 
2. She is in the same beta-carboline family as ibogaine. She is the 2nd highest alkaloid in Caapi. She has a 10.5 hour half-life with peak at 5.25 hours.
 
3. DMT only colors are subdued and dark, but THH brightens the DMT visuals: out of this world impossible bright neon colors are a trait of high dose oral tetrahydroharmine + moderate dose 60 to 70mg+ sublingual or oral HPBCD DMT: neon red-greens, neon orange-blues, neon purple-yellows.
 
4. DMT does not block serotonin on it's own, but THH does...this results in not only stimulation but euphoria in combo with the DMT: and real Ayahuasca visions become apparent...important teamwork. Ibogaine, LSD, mescaline, shrooms, 5-meo-dmt, bufotenin in Amazonian snuffs, all block serotonin, THH blocks serotonin.
 
5. THH has numerous similarities to mescaline, she is like the beta-carboline version of mescaline, few people have used her over 100mg. I have seen the receptorome chart for THH vs. mescaline. She not only blocks serotonin like mescaline, but agonizes all 3 adrenal receptors A1-A3 associated with beauty and aesthetic enhancement, just like mescaline. Beauty enhancement is "over the top" when THH is included, she is diamondlike shimmering in her beauty.
 
Actresses on TV will look like dazzling glowing super-colorful cartoon versions of themselves (just like with high dose cactus tea) only if you include the THH. Researchers have called THH the "tryptamine of the beta-carboline world" and rightly so.
 
6. THH is found in average 150mg in a cup of Caapi based Ayahuasca tea, when 2 cups are drank by some of the more advanced members for evening at the vegetals (UDV, Santo Daime, Shuar Indian) people are consuming around 300mg of THH.
 
7. Music will only sound bad-ass incredible if you include from 150mg to 300mg oral THH with your sublingual or oral DMT.
 
8. This pure THH at 300mg all by herself is extremely visual, she's an isomer of a hormone like substance made in the brain naturally.
 
9. The entry in TIHKAL for 300mg THH is completely wrong, where the unexperienced person compares it to the effects of 100mg harmaline. She is nothing at all like harmaline, and like 69ron once said about the person's comment in TIHKAL, he or she would not be able to tell their ass from their elbow. I agree, what complete nonsense. Dr. Shulgin wrote that he never got the chance to try THH, but wrote that more studies on it are "badly needed."
 
10. professor8 (found here from 11/1/2010 he writes like a poet w/special powers of imagination & expression):
Tetrahydroharmine (THH) has the ability to raise your vibration in a most powerful, yet subtle way. It brings a crystalline prismy texture to spice and adds a super clear watery dimension to Aya, like looking down through 10meters of shimmering Caribbean Sea on clear blue day. It brings a dimension of pure light to the entheogenic experience and encourages entities & intelligences of only the Highest Order. If one is not accustomed to perceiving these experiences with a spiritual perspective most of the nuances & subtleties THH brings on are overlooked and remain unseen and one would better enjoy Harmaline as a house painter chooses a roller over a brush, its about preference & choice.
 
11. Trips (from here on 12/2/2011):
As to how the THH altered the experience -> I find rue extract+DMT to be very similar to mushrooms. I found the THH added to the rue+DMT to shift the experience to a state much closer to that provided by LSD. It was more clear, more energetic, more focused, and when confusion struck it was definitely more "acid-like".
 
The world is moving in the direction of the Left Brain: technology and science. What the world needs is to move in the direction of Right Brain development: empathy, spirituality, connectedness. Compounds like tetrahydroharmine in Caapi could be said to improve emotional intelligence. Is this component of caapi a smart-nutrient for the right side of the brain? you be the judge.
 
At 300mg of THH all by itself, there are heavy open-eyed tracers like lightening flashes, and hours of teaching closed eye visions that start with colored sparkles and fireworks (red, green, yellow, blue) that dart around and progress into full-fledged way-beyond 4k visions with eyes closed that are not only static but often animated like slow and high speed movies, but all one monochrome color like green or blue for me, when you add DMT, the visions then become colored and patterning on animals for example will display their associated colors, DMT also adds on to or builds on top the THH visions, expanding them, but the teachings and insights & visions are credited to the Vine, just as Gayle Highpine writes in linked paper:
 
12. Gayle Highpine (Ayahuasca researcher):
The vine carries the content of the message, the teaching, and the insight. The purpose of drinking Ayahuasca is to receive the message the vine imparts.
 
Tetrahydroharmine or THH ranks very high on the "periodic psychedelic table" among all the known entheogens for inducing realistic way beyond 4k monochrome teaching visions for hours...adding even small amounts of DMT brightens and colorizes the visions, example: reptiles, birds & animals such as serpents/snakes/toucans/parrots/jaguars with patterning show their respective associated colors. Many times I have viewed multi-colored serpents, birds & jaguars several times over hour long CEV periods, serpents are the manifest spirit of Ayahuasca.
 
Daniel Pinchbeck "Breaking Open the Head" (Daniel also states in his book, that Ayahuasca is his favorite entheogen):
For many people, Ayahuasca-a slowed-down low-res interface of the DMT flash-seems to convey strong messages from the natural world, of nature as sentient energy and spirit matter, of the need to protect the planet we have been given.
 
Yage whispers that human beings are meant to be gardeners of this reality, journeyers, storytellers and singers, weavers of the sacred. DMT, on the other hand, conveys no overt human or humane message.
 
Graham Hancock, "Supernatural", pg 428:
My experience with smoked DMT was qualitatively different from the realms and beings Ayahuasca introduced me to. For whereas the Ayahuasca worlds seemed rich, luxurious, and abundant in the transformations of organic and supernatural life, DMT brought me to a world--or to some aspect of a world--that appeared from the outset to be highly artificial, constructed, inorganic, and in essence technological.
 
Gayle Highpine (Ayahuasca researcher):
In the western world, Ayahuasca acquired a new definition: It was now, by definition, the combination of Banisteriopsis caapi and a DMT-containing plant. Ayahuasca became, by definition “orally active DMT.” The first anthropologist to adopt the new definition seems to have been Luis Eduardo Luna in 1984. Luna spent time with Terence McKenna, absorbing his perspective, before beginning his fieldwork. Since then, anthropologists have increasingly adopted this definition and filtered their observations through it. The preeminence of the Ayahuasca vine in the indigenous Amazonian world became the elephant in the living room of Ayahuasca studies, with a tacit agreement to pretend it doesn’t exist.
 
The leaves were Ayahuasca’s “helpers,” I was told, and their purpose was to “brighten and clarify” the visions. The vine is like a cave, and the leaf is like a torch you use to see what is inside the cave. The vine is like a book, and the leaf is like the candle you use to read the book.
 
The vine is like a snowy television set, and the leaf helps to tune in the picture. There was a subtle attitude that the need for strong leaf was the sign of a beginner: An experienced ayahuasquero could see the visions even in low light.
 
Ayahuasca vine is not visionary in the same way as DMT. Visions from vine-only brewsare shadowy, monochromatic, like silhouettes, or curling smoke, or clouds moving across the night sky. It is because their visions are usually monochromatic that vines are classified by the color of vision they produce: white, black, blue, red (in my experience, dark maroon).
 
Snakes, the most common vision on Ayahuasca, are considered the manifest spirit of the vine. Vine visions can be hard to see; in fact, the “visions” may not be visual at all, but auditory or somatic or intuitive. But the vine carries the content of the message, the teaching, and the insight.
 
The leaf helps illuminate the content, but the teachings are credited to the vine. Vine visions are “frequently associated with writing, to a code that is present in visions…or in the ‘books’ where the spirits keep the secrets of the forest.” (Calavia Saez 2011:135).
 
The vine is The Teacher, The Healer, The Guide. The purpose of drinking Ayahuasca is to receive the message the vine imparts. This is why it is the vine, not the leaf, that is classified by the type of vision it gives. “For them the vine is, in truth, a living guide, a friend, a paternal authority” (Weiskopf 2005:104).
 
Listening to the Vine:
While I was living in the village, someone began the process of shamanic apprenticeship. There was a series of ceremonies with brews of special strength for that purpose; brews with enormous quantities of vine. About two to three pounds of fresh vine per person was used (about 25 to 35 times the amount needed for MAOI inhibition). Those were powerful experiences indeed.
 
Although the apprenticeship began with crushingly vine-heavy brews, the more the apprentice progressed, the weaker the brew he would need. He would learn to see the dimmest of visions. If he spent a full two years “fasting,” then eventually even smelling or tasting the brew, even touching an Ayahuasca plant, would be enough to visit her realms. On the other hand, he would learn to navigate the strongest of brews with clear focus, and be undistracted by any amount of DMT fireworks.
 
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Part 1: HPBCD complexed DMT experimental dosage, effects & duration
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How this works: the Hydroxy propyl beta cyclodextrin molecule (HPBCD) has an inner hydrophobic cavity (repels water) which attracts & traps freebase molecules like DMT freebase inside it's tornado shaped cone. The outer cavity is hydrophilic (likes water) and thus makes the DMT molecule water-soluble. HPBCD, being a polysaccharide derived from the enzymatic degradation of starch, improves the penetration of the DMT freebase many factors over (studies show x 4 factors or 400%) into the sublingual mucosa under the tongue.
 
Keep in mind using DMT salts sublingually does not work, and there is no penetration enhancement unless HPBCD is used to complex DMT in the freebase form only. The cyclodextrins have toroidal shapes, with the larger and the smaller openings of the toroid exposing to the solvent secondary and primary hydroxyl groups respectively.
 
You can order HPBCD from China no matter where you live as it is legal, and if you google "Europe + HPBCD" there are a couple places that sell it as well. It is very common in the USA from *mazon or auction sites.
 
My procedure:
1) place 60mg of DMT onto a spoon
2) add 1:1 molar ratio of host drug to HPBCD powder, this means 1:7 mg ratio DMT to HPBCD, use a 1:8 mg ratio DMT to HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
3) this means 60mg dmt placed on spoon, then add 420mg of HPBCD on top DMT, use 480mg HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
4) add 10 to 12 drops of very hot near boiling water to the mix from a coffee mug
5) Knead or crush the HPBCD powder into the dmt using the end of a spoon for 2 minutes
6) Take 150 to 300mg tetrahydroharmine orally around 45 minutes before. Place your tongue onto spoon, the HPBCD DMT glob will all adhere as HPBCD powder forms sticky complexes.
 
Hold under tongue for 12 to 15 minutes, press down with bottom of tongue the whole time to trap sticky liquid complex in the sublingual mucosa. Be sure to use bottom end of tongue to lick any off spoon that is left behind, you want to get it all.
 
At end of 15 minutes, spit out any saliva into a cup instead of swallowing. Spit out any saliva during the 15 minute period as comfort dictates, but keep your tongue pressed down any time you relieve saliva. There is a sting felt but it's so worth enduring for the effects in 22 minutes. The tongue is completely fine afterwards (no burn), and it's as if nothing happened the next day.
 
The combination of THH + DMT simulates true Ayahuasca, but there is zero nausea, zero dizziness, zero queasiness since there is no harmine or DMT going thru stomach and intestines. 22 minutes in there are heavy CEV's of spinning colored geometrics, visions of ancient architecture, animals, aliens, you name it, She seems to tap into the Akashic record of the ether in the Universe, where all past, present, and future is known. Open eyed profound beauty, music sounds incredible.
 
This all lasts for 90 minutes. You can re-dose more HPBCD DMT by two more times, around every 1.5 hours if you want. It remains just as effective as the first dose. The sublingual application is several factors stronger than oral DMT, and I've used oral DMT dozens of times.
 
Oral 300mg THH taken 1 hour earlier + sublingual 60 to 140mg HPBCD DMT journeys (over 44 of them over a year's time). This counts the two subsequent re-doses every 1.5 hour for the evening, for a 4.5 hour total strong journey with super-long afterglow.
 
With oral 150 to 300mg THH + sublingual 60-120mg HPBCD DMT + sublingual 35mg harmine fb, there is zero nausea, zero dizziness, zero un-easy feelings or anxiety, I tolerate this very well compared to oral DMT, extremely pleasurable experience, high spiritual euphoria.
 
First of all there was a deep head space, profound spiritual insights and revelations. I was seeing curtains of visuals in the doorway, closed eye neon spinning & dancing geometrics, music enhancement incredible, out of this world impossible neon colors (like neon yellow-purple) flashing on the walls, some times these colors on the walls would break up into fine lines like lazer beams, and paste themselves like hundreds of beams broadcast on the walls, concentric circle rings in the air, powerful lightening like tracers.
 
Open eyed beauty so over the top & infinite, actresses in movies looked like glowing, dazzling, super-colorful, cartoon versions of themselves, just like with high dose cactus tea, also zero anxiety just like mescaline. Euphoria was powerful, just like with high dose cactus tea.
 
Again with the sublingual: pupil dilation maxed out, strong tryptamine body buzz high frequency, heavy CEV imagery, open eyed beauty profound, music sounds incredible.
 
On my very first 300mg oral THH + sublingual 60mg HPBCD DMT combined with 35mg sublingual harmine fb trip with 2 sublingual re-doses at each 1.5 hour mark (had not used DMT in several months)....all the way till 5am in the morning I was seeing closed eye visions of slow and high speed movies...I saw brightly colored serpents, dungeons I traveled thru, many Mesoamerican pyramids, women of incredible beauty, Japanese landscapes, dancing geometrics, many different animals on a rotating globe, walking on the planet-like globe as it spun, hundreds of visions like slow and high-speed movies over the course of many hours.
 
I wore headphones and listened to music the whole time, as the music sounded just like if I had taken a very strong cactus tea.
 
I saw the interiors of many magnificent homes, exposed like a camera flash went off, then off to the next home interior, bizarre alien looking creatures, I saw ancient ruins but they were seen as they were before they fell apart. All sorts of architectural wonders appeared that I could not make out exactly what time period they were from.
 
All the visions were enchanting & manifested incredible beauty. The multi-colored beautiful serpents kept appearing several times in different forms, as if they have some prominence to do with it all, two of them had shining skin covered in gold scales and intertwined like DNA, reminds me of the Aztec quetzalcoatl myth, the "serpent of precious feathers."
 
...all of these visions were brightly colored due to the sublingual DMT/harmine and oral THH combo all night long..it was one of the most powerful psychedelic experiences of my life...and I've taken Ayahuasca x 70 times, cactus 200 times, etc...I have never had over 5 hours of non-stop CEV visions anything close to what I saw that first night.
 
 
300mg of tetrahydroharmine (THH) is equated to the (CEV) power of 100mg harmaline, but without all the nausea and dizziness. It glows blue under blacklight, like LSD or psilocin & has a metallic-like lingering taste with a 10.5 hour half-life.
 
Don't forget that this should improve the ORAL BIOAVAILABILITY of dmt when combined with a RIMA as well -- this technology has been used to potentiate these freebase drugs ORALLY as well -- this could potentially mean an Ayahuasca experience that is strong in potency. Example: HPBCD improves oral absorption profile for Ofloxacin, a second generation fluroquinolones by 54 to 89 percent.
 
"Sublingual mucosa as a route for systemic drug delivery" by Narang & Sharma 2010:
 
As you can see from this sublingual viagra study, even 50 to 100mg doses can be administered under the tongue, the authors noting that less of the drug was required, and that it began working in only one half the normal time of an oral dose:
 
"The start of pharmacological activity after sublingual administration of sildenafil citrate in 30 patients affected by erectile dysfunction." by Siati & Franzolin 2003:
 
Tetrahydroharmine on it's own will also yield the same type visions as harmaline, it just takes more of it. For example, around 300mg of THH will yield the same visions as about 100mg harmaline...even if the THH dose is split in two over several hours, the visions will still be apparent some time after the 2nd dose takes effect, the doses are additive.
 
THH in the caapi also seems to strongly activate the right hand hemisphere of the brain-- the side that performs tasks that have do with creativity and the arts, feelings, visualizations, imagination, holistic thinking & intuition, empathy, spirituality & connectedness. Researchers found that the right side of the brain lit up in brain scans of people who took LSD, mescaline, or mushrooms. This includes tetrahydroharmine. The world is largely moving in the direction of the Left Brain: technology and science. What the world needs is to move in the direction of Right Brain development.
 
Quote from TIHKAL by Dr. Shulgin "More studies on tetrahydroharmine are absolutely imperative."
 
References:
 
Dennis Mckenna Ph.D:
Thus, tetrahydroharmine may prolong the half-life of DMT by blocking it's intraneuronal uptake, and hence, its inactivation by MAO, localized in mitochondria within the neuron.
I have years of experience with pure tetrahydroharmine, and it does indeed do this very well.
 
Jamie, posted : 11/23/2012 8:29:28 PM:
You can't compare sublingual or oral either..20-30mg sublingual harmine is enough to activate sublingual DMT and cause effects on it's own. 20mg sublingual is probably comparable to 200mg oral.
I use 35mg freebase harmine sublingually along with the sublingual HPBCD complexed DMT, 35mg sublingual has the power of x6 or 210mg oral harmine, but without the dizziness and un-easy feelings you often feel with an oral dose.
 
Dr. Narang:
The absorption of drugs through the sublingual route is 3 to 10 times greater than oral route and is surpassed by hypodermic injection. Sublingual mucosa under tongue is only 100 to 200 microns thick.
In over 44 total sublingual experiences over a year's time, this sublingual route is many times more potent than oral DMT. The only way I use it.
 
Pic1: How to mix the DMT, HPBCD, and drops of very hot water on a spoon.
 
Pic2: 1kg container of HPBCD from China for cheap. 2-hydroxy-propyl-beta-cyclodextrin is the more common form available, works the exact same.
 
Pic3: Sublingual mucosa under tongue only 100 to 200 microns thick.
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Stay true to yourself, Love, Peace and Music
 
sublingual Ayahuasca.PNG
 
 
HPBCD.PNG
 
sublingual mucosa only 100 to 200 microns thick.PNG
 

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#2 tregar

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Posted 02 January 2022 - 11:58 AM

In closing, complete instructions and pictures all updated for 1-1-2022 on sublingual HPBCD DMT & summary of over 44 sublingual experiences in a year's time (bottom of post #1), these experiences all must stronger than oral DMT by many factors. Zero nausea, zero dizziness, zero anxiety or un-easy feelings, deep head space, highly visual, strong open eyed and CEV's of spinning & dancing geometrics & real Ayahuasca visions, incredible music enhancement, way over the top open eyed beauty, neon colorful & highly euphoric, see trip reports bottom of post #1...will continue to use for the rest of my life, highly recommend.

My procedure:
1) place 60mg of DMT onto a spoon
2) add 1:1 molar ratio of host drug to HPBCD powder, this means 1:7 mg ratio DMT to HPBCD, use a 1:8 mg ratio DMT to HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
3) this means 60mg dmt placed on spoon, then add 420mg of HPBCD on top DMT, use 480mg HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
4) add 10 drops of very hot near boiling water to the mix from a nearby microwaved coffee mug for DMT doses of 90mg or below, use 12 drops of boiling hot water to mix DMT doses over 90mg (such as 100 to 120mg). 60mg DMT = +3 Shulgin level strength, 90 to 120mg = +5 Shulgin level life changing strength.
5) Knead or crush the HPBCD powder into the dmt using the end of a spoon for 2 minutes, scrape & mix everything back and forth hard using your muscles. This is how scientist pre-pare these complexes by kneading.
6) Hold a lighter under the spoon with flame around an inch or less away to heat up spoon for around 15 seconds or so to 110 degree F or more, so that complete dissolution or dissolving takes place, after heating up, mix the contents a little bit more before using.
see pics.
6) Take 150 to 300mg tetrahydroharmine orally around 45 minutes before. Place 35mg of freebase harmine under your tongue. Then place bottom of your tongue onto HPBCD complexed DMT spoon, the HPBCD DMT glob will all adhere as HPBCD powder forms sticky complexes. Be sure to take the 35mg harmine and HPBCD DMT under tongue all at the exact same time in order to activate the DMT strongly.

Hold under tongue for 10 to 12 or 15 minutes depending on dosage, press down with bottom of tongue the whole time to trap sticky liquid complex in the sublingual mucosa. Be sure to use bottom end of tongue to lick any off spoon that is left behind, you want to get it all.

At end of 15 minutes, spit out any saliva into a cup instead of swallowing. Gently relieve any saliva during the 15 minute period as comfort dictates by leaning your head forward and spitting into a cup, but keep your tongue pressed down any time you relieve saliva. There is a mild to moderate sting felt but it's so worth enduring for the effects in 22 minutes. The sting does not bother me at all. The tongue is completely fine afterwards (no burn), and it's as if nothing happened the next day.

Pic 1: 300mg pure white tetrahydroharmine taken 45 minutes earlier orally, 35mg brown freebase harmine taken sublingually at same time (under tongue) as 90mg DMT complexed to (90 x 7 = 630mg HPBCD, use 90 x 8 = 720mg if using the more common 2-HPBCD) in 10 drops of boiling hot water.

Pic 5: Notice Bic lighter, dropper, mug of microwaved boiling hot water, 90mg DMT was added to spoon with (90 x 7 = 630mg plain white HPBCD) and crushed + mixed well for 2 minutes on the spoon (scraping all together back & forth hard using your muscles) using the end of another spoon in 10 drops of boiling hot water, then lighter held under spoon for 15 seconds or so to complete the dissolution of the DMT into the HPBCD. After heating up, mix the contents a little bit more before using.

Pic 3: Notice how well the DMT dissolved or complexed into the HPBCD. Make sure your 35mg harmine fb is under your tongue 1st, then place your tongue onto spoon, the sticky HPBCD complexed DMT will all adhere, get ready for a very strong journey that begins in 22 minutes, and lasts for 90 minutes, at which time you can re-dose more sublingual harmine + HPBCD DMT up to 2 more times, each dose just as strong as 1st dose, for a 4.5 hour long journey with super-long afterglow beyond that. No need to ever take more THH as it has a half-life of 10.5 hours with peak at 5.25 hours.

 

sublingual HPBCD DMT pics.PNG


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#3 tregar

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Posted 03 January 2022 - 05:58 AM

Parts 2 thru 14 continued here: 

 

HPBCD DMT sublingually active under tongue - Pharmahuasca - Welcome to the DMT-Nexus

hxxps://www.dmt-nexus.me/forum/default.aspx?g=posts&t=96861


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#4 tregar

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Posted 03 January 2022 - 11:57 AM

Part 5: Chemist Patrick Arnold's HPBCD complexed prohormones for sublingual use (millions of dollars in sales) & bloodwork studies

Several years ago, before "prohormones" were banned (they were legal for 10 years), there was a company called "Ergopharm" ran by chemist Patrick Arnold. Ergopharm had sales in the millions due to their hot selling HPBCD complexed 4-androstenediol (Cyclodiol, see attached pic).

Patent granted to Patrick Arnold:
https://en.wikipedia...Patrick_Arnold

In 2001 Arnold's company introduced the prohormone 4-Androstenediol, under the marketing name 4-AD. 4-AD is a prohormone that is easily converted by the body into testosterone at a rate of 95%, and it sold well. He is the chemist who created hydroxypropyl-beta-cyclodextrin complexed diols such as Cyclo-Diol™ and Cyclo-Nordiol™.

https://thinksteroid...rick-arnold-11/
hxxps://thinksteroids.com/articles/ask-patrick-arnold-11/

I bought and used the sublingual HPBCD cyclodiol when it became available and it was very effective, had my testosterone level checked with a blood test at the local labcore one hour after administering the sublingual powder under my tongue (dissolved in less than 10 minutes) and it was 3,500 ng/dl ! when my normal level was 600ng/dl. Highest measured normal levels in men are around 1200 ng/dl. The blood test cost me $70.00. The sublingual HPBCD complexed pro-hormone would cause the 4-ad to enter the bloodstream via sublingual mucosa under tongue, and convert to testosterone via enzyme activity once in the bloodstream. Patrick invented the pro-hormone 4-ad or 4-androstenediol, which converts to testosterone at a rate of 95%.

Patrick Arnold's sublingual powder of HPBCD complexed 4-AD could be grabbed from the bottle with a pre-measured scooper, and the powder need only be held under tongue for less than 10 minutes. The HPBCD complexed DMT on the other hand dissolves in 15 minutes or less under tongue, as it is a slightly higher dosage.

Before Patrick started his company, he used to post on "deja-news" bodybuilding news group (defunct now but bought out and owned currently by Google) and would explain to bodybuilders how to complex HPBCD powder to 4-androstenediol at home using a spoon, drops of hot water, end of another spoon to mix and crush all ingredients together, lighter to heat up, etc. I learned his technique back then, and created my own HPBCD complexed 4-ad for sublingual use just like hundreds of other bodybuilders who read his postings and asked questions daily, there are logs of this that would fill up a book.

Later, the pharmaceutical industry picked up on his idea and started marketing sublingual HPBCD testosterone base (read the 3 studies in the link above from Patrick's column at MesoRx midway thru), which worked remarkably well to raise the testosterone of hypogonadal men to the high-normal level when absorbed under the tongue.

Pic: Ergopharm's hot selling cyclodiol powder, HPBCD complexed 4-androstenediol, when used sublingually, converted into testoserone at a rate of 95% via enzyme activity once it quickly entered the bloodstream from the sublingual mucosa.
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Attached 1: Sublingual Mucosa as a route for systemic drug delivery by Narang, Sharma, 2010.
 
Attached 2: Thermodynamic properties of hydroxypropyl‑β‑cyclodextrin/guest interaction: a survey of recent studies by D'Aria, Pagano, Giancola, 2021.
 
Ergopharm's hot selling cyclodiol powder (HPBCD complexed pro-hormones).JPG
 
 

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#5 tregar

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Posted 04 January 2022 - 08:19 AM

Part 2: receptorome chart & explanation
 
This is why I suggest taking the DMT with tetrahydroharmine (as found in true Ayahuasca):
 
Thomas S. Ray, Psychedelics and the Human Receptorome (2010):
hxxp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009019
Breadth of Receptor Binding, 4.00=max or "off the charts", 0.00=min
LSD: 5ht1a = 3.73, DMT: = 0.00, psilocin = 2.88, mescaline = 3.61, 5-meo-DMT: = 4.00 (make up >80% of brain 5-ht)
LSD: 5ht1b = 4.00, DMT: = 0.00, psilocin = 2.19, mescaline = 0.00, 5-meo-DMT: = 2.41
LSD: 5ht1d = 3.70, DMT: = 3.91, psilocin = 3.40, mescaline = 0.00, 5-meo-DMT: = 3.48
LSD: 5ht1e = 2.62, DMT: = 3.28, psilocin = 3.03, mescaline = 3.16, 5-meo-DMT: = 1.72
LSD: 5ht2a = 3.54, DMT: = 2.58, psilocin = 2.14, mescaline = 0.00, 5-meo-DMT: = 0.98
LSD: 5ht2b = 3.11, DMT: = 3.91, psilocin = 4.00, mescaline = 3.97, 5-meo-DMT: = 0.69 (sensual & entactogenic)
LSD: 5ht2c = 3.11, DMT: = 3.42, psilocin = 2.52, mescaline = 0.00, 5-meo-DMT: = 1.55
LSD: 5ht5a = 3.64, DMT: = 3.16, psilocin = 2.83, mescaline = 0.00, 5-meo-DMT: = 1.84
LSD: -5ht6 = 3.75, DMT: = 3.35, psilocin = 2.82, mescaline = 0.00, 5-meo-DMT: = 2.73
LSD: -5ht7 = 3.77, DMT: = 4.00, psilocin = 2.82, mescaline = 0.00, 5-meo-DMT: = 3.69 (novelty & new ideas)
LSD: ---D1 = 2.34, DMT: = 3.51, psilocin = 3.37, mescaline = 0.00, 5-meo-DMT: = 2.38
LSD: -A-2A = 2.93, DMT: = 2.75, psilocin = 1.36, mescaline = 2.92, 5-meo-DMT: = 0.00 (aesthetic/beauty adrenal a2a)
LSD: -A-2B = 0.00, DMT: = 3.53, psilocin = 1.57, mescaline = 0.00, 5-meo-DMT: = 0.86 (aesthetic/beauty adrenal a2b)
LSD: -A-2C = 0.00, DMT: = 3.53, psilocin = 1.03, mescaline = 4.00, 5-meo-DMT: = 1.57 (aesthetic/beauty adrenal a2c)
 
2011 Thomas S. Ray study: Breadth of Receptor Binding, 4.00=max, 0.00=min
LSD: 5ht1a = 3.73, DMT: = 0.00, psilocin = 2.88, mescaline = 3.61, 5-meo-DMT: = 4.00, (these serotonin filters/gates/barriers/doors make up >80% of brain 5-ht & are broken down when 5-ht1a is agonized)
 
This study from Mol Pharmacol. 1988 Feb;33(2):178-86. backs up the above study from Thomas S. Ray:
 
Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture. https://www.ncbi.nlm.../pubmed/2828913
5-HT1A agonist: All the tryptamine derivatives substituted in position 5 of the indol were potent agonists [5-HT, 5-CT, 5-MeO-N,N-DMT, 5-methoxytryptamine, and bufotenine (5-ho-DMT)],
 
whereas tryptamine, N-methyltryptamine, and N,N-dimethyltryptamine (DMT) were poor agonists.
 
Dr. Nichols (Heffter.org LSD paper):
LSD has very strong potency in blocking the action of serotonin. LSD is strongly "anti-serotonin". The morpholide lysergamide cousin had only about 1/10th the potency in blocking serotonin. Of the 5 diferent dialkylamides we studied LSD was the most potent and specific serotonin antagonist.5-ht1a makes up >80% of brain 5-ht receptors

 

An example of the importance of adding the serotonin reuptake inhibition properties of 5-meo-dmt for example to dmt (which has poor 5-ht1 reuptake properites on it's own) is shown below. This is the same way the snuff's are used in the amazon, as they naturally combine dmt with additives which cause the reuptake of 5-ht like bufotenin for example.
 
Oroc's experiment of combining 5-meo-dmt with DMT sounds imho very much like a short beautiful transcendental Ayahuasca experience, from his book "Tryptamine Palace":
 
DMT + tiny amounts of 5-meo-dmt [perhaps similar theoretically to Amazonian snuffs which have a makeup of 7.4% bufotenin (potent 5-ht1a agonist), 0.04% 5-MeO-DMT (potent 5-ht1a agonist) & 0.16% DMT (poor potency as 5-ht1a agonist):
As an experiment (and in a foreign land) I smoked the last of the Bufo alvarius venom (the story of whose collection is described within the pages of Tryptamine Palace) with some ‘regular’ DMT (extracted from Jurema Preta.). In the vast majority of my early nigerine (DMT) experiences, I encountered visual fields of ‘dots’ that would come together to form images, much like the pointillism style of painting developed by Georges Seurat or the Australian Aboriginal song-line paintings.
 
** With the addition of the 5-MeO-DMT containing toad-venom to the DMT however, the visual characteristic was completely different and totally unique to my experiences so far. On this occasion there was a complete lack of ‘dots’ or ‘points’ of any kind, the fine lines of the constantly changing imagery were like those painted with a single-hair brush on Tibetan thangkas and due to the overwhelming artistry of what I was seeing, I could only think of the vaulted ceiling of the Sistine Chapel in comparison.
 
Sistene Chapel: This was without a doubt the most ‘visionary’ experience I have ever been fortunate enough to encounter and I lay there with my eyes shut watching the most fantastic parade of the Collective Unconsciousness imaginable, wishing that it would never end, and as I sit here now I can not even describe one tiny corner of it, since every image in the multitude of imagery was in such constant motion that they defied all but a glimpse. And then moments later, like a tent collapsing when its ropes are cut, the vision is gone. Leaving only a struggle of words to explain it, since nothing before or after has come close to this experiences visual majesty.
 
As we go thru day to day life, the 5-ht1a brain serotonin filters (gates, or day to day survival filters as I like to call them) which make up over 80% of brain 5-ht are in place so that we will not be overwhelmed by the perception of the way things would appear to an un-filtered mind, or "Mind at Large" as Aldous Huxley describes it in "Doors of Perception" as "infinite or eternal". He also referred to the visions as coming from "the other world" in his book "Moksha". I prefer to think of it in similar terms as well "the spirit world" or "the other world".
 
5-ht1a inhibition by entheogens (in green above) theoretically cause this filter system to be lifted, and the infinite mind to manifest in combination with oral dmt with the tetrahydroharmine providing the 5-ht1a inhibition & additional adrenal system agonization (A2A thru A2C), just as bufotenine in snuff's provide the 5-ht1a inhibition combined with the dmt in the snuff's, resulting in a 3 hour experience ie both examples of Teamwork on how these entheogens are used traditionally in the Amazon.
 
Thomas S. Ray's study shows a value of 3.57 at SERT for Ibogaine (4.00 is max). Ibogaine has been shown to inhibit serotonin transporter (SERT) noncompetitively, in contrast to all other known inhibitors, which are competitive with substrate. Ibogaine inhibits both serotonin and dopamine reuptake transporters, it is an SDRI or serotonin & dopamine reuptake inhibitor.
 
Tetrahydroharmine is a serotonin reuptake inhibitor, it is an SRI found in caapi. In other words, both are strong serotonin reuptake inhibitors which inhibit over 80% of brain 5-ht at 5-ht1a.
 
In contrast, as an example, Cocaethylene (coca leaf tea bags soaked in wine, the orally active & potent ingredient formed in the liver from cocaine + ethanol in the 1860's "Vin Mariani" wine popular with both Popes, Thomas Edison and scores of other famous people) increases the levels of serotonergic, noradrenergic, and dopaminergic neurotransmission in the brain by inhibiting the action of the serotonin transporter, norepinephrine transporter, and dopamine transporter. These pharmacological properties make cocaethylene a serotonin-norepinephrine-dopamine reuptake inhibitor [SNDRI; also known as a "triple reuptake inhibitor"].
 
Cocaethylene has a higher affinity for the dopamine transporter than does cocaine, but has a lower affinity for the serotonin and norepinephrine transporters. In McCance-Katz et alia's 1993 study cocaethylene "produced greater subjective ratings of 'High' in comparison with administration of cocaine or alcohol alone."
 
69ron on harmalas:
Ayahuasca is Banisteriopsis caapi. It contains mostly harmine and tetrahydroharmine (THH). B. caapi itself contains no DMT and can be used as is to produce visionary states that are like mental day dreams which lack true visual content. Often admixtures are used to increase the visual content of the ayahuasca dreams. Most admixture plants contain DMT.
 
Harmine & THH used alone, can produce a mild dreamy psychedelic experience in which daydreams or lucid dreams can be experienced if the user chooses to do so. These dreams from the harmalas alone are vague and lack visual content, but usually have story lines and can be quite complex just like a real dream. The harmalas allow one to go in and out of dream consciousness at will. It takes some practice to learn how to enter a lucid dream with the harmalas alone. The harmalas won’t make you enter a lucid dream. You have to do it yourself by allowing your mind to drift off into a lucid dream.
 
DMT used alone, produces an intense visual experience, often very chaotic and fast moving, and quite amazing to watch. The visions of DMT alone usually lack meaningful content. The DMT visions are often just constantly morphing colors and shapes. Most of it makes absolutely no sense. Rarely will the visuals present to you a full blown dream with people, places, a story line, etc. But this does sometimes happen. But usually you just get a bunch of bazaar visions that are difficult to understand.
 
When combined, as in Ayahuasca, the harmalas brings a dreamy quality to the DMT experience that makes it more like one is experiencing an actual dream, not just a bunch of fancy colors. With the two together, you have the visuals of DMT, plus the dream content of the harmalas. The harmalas are the boss here in this combination if used in Ayahuasca proportions where the harmalas are not just used as an MAOI but is used specifically to allow dream consciousness to be entered by the user. DMT is just an additive used to increase the visual portion of the harmala induced dreams.
 
Using harmalas in very low doses, just as an MAOI, is not the same as using properly made Ayahuasca. If the harmalas are used in low doses just for it’s MAOI effects, the trip lacks dream content and is just a bunch of bazaar DMT visual effects. This is not Ayahuasca-like, it’s just orally activated DMT. That’s not the same. Its true that some Ayahuasca is prepared this way, but such Ayahuasca is considered inferior by most natives. With Ayahuasca, the DMT is just an additive, not the main course. This is why Ayahausca made with only caapi is still called Ayahuasca and considered nearly as powerful as Ayahuasca made with additive plants containing DMT.
 
This is something a lot of people don’t get. Ayahuasca is not simple orally activated DMT. It is the dream consciousness effects of the harmalas that are at play in Ayahuasca. In order to experience lucid dreams from harmine + THH without DMT, you need to practice a lot. But once you know how to do it, you don’t need DMT added to it anymore, unless you want the extra visual depth that DMT adds to the dreams.
 
So, “Dmt Or Ayahuasca?”, well that question is a personal question. Some people prefer DMT-less ayahuasca. Some people prefer just orally activated DMT. Some people prefer Ayahuasca with a side order of DMT. Some people prefer the truly bazaar effects of smoked DMT alone.
 
My personal opinion is that DMT alone is FUN and can be quite frightening. It’s like a roller coaster ride and I like roller coasters. But don’t expect a deep meaningful life changing experience from it. Its pure visual FUN and nothing more. If I want a more meaningful experience I’d use an oral Ayahuasca extract, or a smoked Yopo extract (not as effective as ayahuasca because Yopo is low on harmala-like alkaloids)
 
Authentic Ayahuasca, high in harmine & THH, and low on DMT, is like entering a full blown 3D dream with dream characters, storylines, etc. This can be a life changing experience. It’s more like sitting in a theater for several hours absorbing a story that’s meaningful because its about you. You leave with memories of places, things, people, etc., and possibly a new view on life.

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#6 tregar

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Posted 04 January 2022 - 08:21 AM

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Part 3: 300mg Tetrahydroharmine (THH) teaching visions all by itself
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The Ayahuasca closed eye visions using 150 to 300mg tetrahydroharmine or THH and HPBCD complexed DMT (30mg on up) together surpass in magnificence anything I have ever seen in reality or in works of art.
 
With open eyes, all spiritual things such as nature, art, female form, beauty, joy, take on significant meaning with infinite beauty, just like with cactus or LSD. Extraordinary beauty is manifested with open eyes and with the visions one sees with closed eyes. Impossible neon-like colors are seen that don't exist on this Earth.
 
The existence of a higher spiritual plane is recognized to which insight can and must be gained, yet it does not reject the mundane reality as inferior or empty. This joyous embracement of the world of form leads to words like infinite pleasure, beauty and joy. This loving reappraisal of the worldly forms leads the way to higher divine planes.
 
At 9pm one night, took another 100mg of THH, for a total of 350mg of THH for afternoon & night, before I fell asleep, I watched dream-like monochrome imagery (usually always in green or blue for me) as the THH was still working...I viewed mind-blowing vistas--grand architecture and cities, a bookshelf full of ancient books, a view of the gardens in front of what looked like Versailles, France.
 
I traveled down a street in Midieval period where I saw beautiful women walking along the street, I could make out the houses & markets along the street. Many of these visions are like slow speed movies being played, way beyond 4k, highly detailed...true Ayahuasca visions...this always happens when I take at least 300mg or more of tetrahydroharmine during the late afternoon/early night. This is one of the best parts of the journey imho.
 
I've taken 300mg of THH on it's own many times and for hours with eyes closed I view endless dream-like visions, like slow and high speed movies being played for several hours...totally unlike normal dreams, she seems to tap into the "Akashic record" of the universe, the ether where all events, past, present, and future are stored...she shows you artwork, architecture, nature, culture, fantasy, history, the future, spiritual, supernatural. The visions are also characterized by the extraordinary beauty that they manifest.
 
Tetrahydroharmine was called by one researcher "the tryptamine of the beta-carboline world" to give an example of her remarkable visionary properties. She is an isomer of a hormonal-like compound found in the brain naturally, she is what gives Ayahuasca her telapathine or telethapy properties and CEV dream-like visionary power.
 
300mg THH in Caapi is just as visual as 100mg harmaline but without the nausea and dizziness. At 300mg she gives one several hours of incredible closed eye realistic visions, this places her very high on the "psychedelic periodic table" for visions compared to just about any other entheogen.
 
It's like entering a university, she teaches you for hours with not only sequential visions one after another, but visions seen in continuous slow and high speed movies. She tells you a story for a long period. There is a theme to it all each time, the beautiful visions never repeat session to session. I only rarely go beyond 300mg THH, as a little dizziness sets in above 300mg for sure. No dizziness at 250mg, only a tiny bit at 300mg.
 
Several weeks ago, after drinking 300mg tetrahydroharmine, I saw the interior decorations of palaces, the checkered floors, the beautiful windows and furniture, the winding stair cases, I was blown away.
 
I've seen sacred temples for religious worship, beautiful animals and super fine women, birds of all kinds, even the lost city of Atlantis, I was taken in for a bird's eye view, zooming in from way above to all the way down into the city center.
 
Caapi tells a story when you drink it with eyes closed, she teaches you things, the most beautiful "realistic visions" that no other entheogen comes close to showing you, these realistic visions go on forever with Caapi, I can recline and watch for 2 hours or more the visions, the visions are quite powerful. You can take additional THH hours later to bring back the visions again for another 45 minutes, the doses are additive.
 
Pic: 300mg of THH showed me closed eye vision of gardens at Versailles, France
 
300mg THH showed me visions of gardens at Versailles, France.JPG

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Posted 04 January 2022 - 08:22 AM

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Part 4: Tetrahydroharmine receptorome similarities to mescaline; potentiates cactus & safety note
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A little off topic, but I think tetrahydroharmine is a pretty special compound. I've used 250mg of it to potentiate cactus to very strong levels, it makes a 12" medium san pedro cactus tea which may contain around 250mg mescaline feel like an X-large 12" thick san pedro cactus containing around 400mg mescaline. It makes a 12" thick bridgesii cactus feel closer to a tea made with a 12" bridgesii cactus along with an extra 6" piece.
 
In the data I've seen for THH, it strongly blocks serotonin just like cactus, but also agonizes the adrenal A2A thru A2C receptors (the receptors associated with aesthetics & beauty), just like mescaline has been shown to do receptorome wise, explaining perhaps why they "overlap" so well. THH being able to make mescaline in cactus feel much stronger than it really is. Anyone who has ever taken cactus or high dose THH knows the appreciation for beauty experienced is "over the top".
 
But you have to stagger the THH from the cactus by taking the tetrahydroharmine around an hour after the cactus is taken, that way any minor maoi's or rima's in the cactus won't interact with the SRI which is THH, which can result in a faster heartbeat for a few hours which has happened to me before...so long as you take it later, it potentiates the cactus quite incredibly...it feels like I've taken 400mg of mescaline containing cactus tea when it's really only 250mg mescaline containing cactus, and they both lasts around 6 hours with super strong activity, so they wind down at around the same time. I have around 7 months experience combining the two, giving myself around 2 weeks apart from journeys.
 
It works so well, I won't take cactus any other way from now on. I get much more mileage from cactus this way. Visuals and visions are insane, music is so good sounding, you would think you were an alien experiencing sound and music for the very first time, every instrument stands out on it's own, like hearing a track for the very first time.
 
Always take the san pedro, bridgesii or torch cactus first (they all contain trace maoi like actives)...then take the THH one hour later, in that order, then the journey is pure bliss and no negative interactions. Beautiful combo beyond belief, just like the combo of THH + LSD or THH + mushrooms.

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Posted 04 January 2022 - 08:23 AM

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Part 6: Dr. Narang: "with sublingual or "under the tongue" better than buccal, gingival & palatal
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With Insufflation, sublingual or rectal, DMT is not broken down by monoamine oxidase.
 
However, tetrahydroharmine and harmine both work to block the inactivation of DMT by MAO localized within the mitochondria of the cells of the brain, this also greatly extends the half-life of the DMT.
 
See above paper from Narang et al, Intl J Pharm Sci, Vol 3, Suupl 2, 2011, 18-22:
"With sublingual or "under the tongue", the mucosea thickness is only 100-200, high permeability with rich blood supply, much better than buccal or gingival & palatal, 200, 250, 500 micrometer respectively, shuttling the drug directly to bloodstream." The DMT is not broken down via monamine oxidase whatsoever this way. It avoids the liver and first pass metabolism. The drug is rapidly absorbed via the rich blood supply vessels under the tongue rather than being broken down in the digestive track via the enzyme monamine oxidase. According to paper: "Sublingually administered drugs reach directly in to the blood stream through the ventral surface of the tongue and floor of the mouth. The drug solutes are rapidly absorbed into the reticulated vein which lies underneath the oral mucosa, and transported through the facial veins, internal jugular vein, and braciocephalic vein and then drained in to systemic circulation."
 
According to paper, "the absorption of drugs through the sublingual route is 3 to 10 times greater than oral route and is surpassed by hypodermic injection. Peak blood levels of most products administered sublingually are achieved within 10 to 15 minutes, which is generally much faster than when those same drugs are ingested orally." This has been my experience as well, after 10 minutes of sublingual under tongue application, 5 minutes after the 10 minute sublingual absorption, the DMT rush is felt, followed by 60 to 90 minutes of entheogenic activity. According to paper, "sublingual absorption of drugs is efficient. The percent of each dose absorbed is generally higher than that achieved by means of oral ingestion."
 
Smoked: If DMT is smoked, the maximal effects last for a short period of time (5 to 30 minutes, dose-dependent). The onset after inhalation is very fast (less than 45 seconds) and maximal effects are reached within about a minute.
 
Insufflation & Sublingual absorption via Oral Mucosa (under tongue): When DMT is insufflated (snorted through the nostrils) or absorbed sublingually the duration is markedly increased.
 
Injection: Injected DMT produces an experience similar to inhalation in duration, intensity, and characteristics.
 
Oral ingestion: DMT, which is broken down by the digestive enzyme monoamine oxidase, is practically inactive if taken orally, unless combined with a monoamine oxidase inhibitor (MAOI).

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Posted 04 January 2022 - 08:25 AM

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Part 7: a little bit on my 70 Ayahuasca experiences, doses & visions
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FYI: The THH is an SRI (serotonin reuptake inhibitor with significant adrenal activity at A2A thru A2C receptors, similar to mescaline in that regard), it has super weak MAOI activity (see Wikipedia on tetrahydroharmine).
 
I looked up the data comparing RIMA activity of THH to harmine from a lab supplier who gave the data, and they referenced THH as only having around 1/100th the RIMA strength of harmine, practically non-existent strength as a RIMA. That would mean it would take 20,000mg of THH to equal 200mg of harmine in RIMA strength. Harmine & harmaline however have significant RIMA/MAOI activity.
 
How to best describe THH or tetrahydroharmine:
 
THH alone (200 to 300mg) with open eyes = everything is brighter and extremely colorful, beauty enhancement is over the top...neon-diamondlike is my best description, like looking down thru several meters of clear blue ocean water on a bright sunny day, just like professor8 describes it. A study done once on the UDV found that brews with high levels of tetrahydroharmine were preferred over all other brews, they found the "dmt was not the main attraction" but actually brews high in THH, fascinating study.
 
With 300mg THH, closed eye dream-like Ayahuasca visions actually form with closed eyes that begin with colored sparkles and geometric dots and ziggly lines in orange, green, and blue that dart around and then progress to the monochrome visions for 1.5 to 2 hours, These visions are WAY beyond 4k, and highly detailed. The DMT seems to add color and brightness to the visions. The DMT also of course adds strong psychedelic alterations & activity to the journey and enhances the quality of music in combo with THH, music sounds incredible as mentioned before for several hours, especially if you keep taking the sublingual DMT around once every 1.5 hour for the next 4.5 hours.
 
Years ago, I took DMT freebase (70 to 90mg) with harmine and THH pharmahuasca at least a dozen times, and found it mild at best (on a Shulgin scale of 1 to 5, they were all +3 experiences). I even tried to dissolve it into coca cola and citric acid in hot water to make it absorb better as the salt, but it only slightly increased the strength.
 
After that I switched to taking 30 to 35 grams of Hawaiian psychotria boiled down to a couple oz, then added the harmine + thh to the 2oz of hot pychotria tea....well that blew my mind CONSISTENTLY for many years, as I continued to use it over 65 times! All of the experiences were +5, very strong indeed, much stronger than the freebase used dmt.
 
This agrees with what I read from clearlight:
Clearlight experiments that involved several people found the leaf brew form superior to extracted actives, they found the leaf brews very strong and powerful & clairavoyant (+5 Shulgin scale), while they mentioned that the extracted actives were mild (+3 Shulgin scale) at best, even up to 100mg. Again, this is poorly understood.
 
Even Jonathan Ott found that in his 20 experiments posted in his book "Ayahuasca Analogues", that none of his later experiments with extracted actives quite matched the power of his 1st actual Ayahuasca brewed with caapi and good real leaf (experiment #1), he had no explanation for this. He did however find 70mg to be close to it, but still not the same.
 
From "Articulations, On the Utilisation and Meanings of Psychedelics" (2015) by Julian Palmer:
Modern day researchers, spearheaded by people such as myself, have realized that Jonathan Ott's calculations fall short of what most explorers need for a truly visionary experience. Even with a strong harmine/Banisteriopsis caapi dosage, 30-60mg of dmt is not sufficient to produce significant visionary effects in most people. So if fact, a dosage of 30-40mg of dmt is where tryptamine-like effects just begin to occur for most people, and 10-25mg dmt is not really noticeable above the gentle psychoactive effects of the harmine.
 
Each person is different and for some rare individuals, 30-40mg may be about as much dmt as they wish to take--but most people need at least 60-80mg for sufficient psychoactive effects and even at this dosage, you generally cannot expect a full-blown visionary experience, even when using a strong dose of 4 grams of syrian rue or 100 grams of strong caapi vine. Also, it should be pointed out that going beyond 4 grams of syrian rue (around 200-280mg of harmaline) or 100 grams of strong caapi vine (150--250mg of harmine) can increase the negative effects of these beta-carbolines--which include a feeling of heaviness, pressure in the head, inability to walk properly, more purging and perhaps more of an emphasis on bodily processes.
 
An oral dosage of 100mg of dmt is where the visionary qualities really begin to occur, for most people say when they are taking 3 grams of syrian rue or 80 grams of strong vine, and in context, 40-60 grams of strong vine is enough to fully mao inhibit most people.
 
I would say to neophyte explorers to tread carefully, and to slowly increase your dmt dosage in increments: perhaps starting at 60mg, going to 100mg, then 150mg. Some people are going to find 100mg of dmt to be exceedingly strong, and it will perhaps give them an experience they did not feel ready for.
 
It came to my attention after an embarrassing number of years, that taking freebase crystal DMT orally was not as potent, colourful, or clear as taking the equivalent amount of DMT in a tea that was brewed from the plant. For many years, I couldn't see how there could be a difference, but after doing some comparisons, it was obvious that the tea was much better, and the experiences resulting from the crystalline extract were inferior.
 
You could take twice or even three times as much DMT crystal as the equivalent in brew, and the experience from the crystal would never be as bright or full as that from the tea. Why could this be?
 
With extracted dmt, with chemicals used it would appear that some dimensions and qualities of the tryptamine molecules are compromised. Also, there is the factor of isolating the alkaloids from the rest of the plant. For example, there are very few people who say that extracted pure mescaline from the cactus is as potent of full bodied compared to when they take the tea made from the cactus flesh.
 
When making a tea from the whole plant, you are extracting the essence of the plant intelligence from its very flesh, not just isolating the alkaloids. In the alchemic method "Spagyrics" developed by Paracelsus, often considered the father of modern medicine, the ashes of the plant are commonly burnt and then blended back into an alcohol-extracted tincture. Friends who have experimented with this procedure report that a Spagyric tincture of Ayahuasca is much more potent than a normal tea prepared from the same amount of Ayahuasca vine.
 
However, at this point, I have noticed that ALL the dried Hawaiian psychotria is extinct, and is no longer available. But no worries, HPBCD complexed DMT feels the void very well, and is much more potent than plain DMT which is absorbed poorly via the oral or sublingual route. Studies show HPBCD when complexed to drugs like DMT improve drug penetration x 4 factors or 400% when used sublingually or orally.
 
In one past journey with 30g Hawaiian psychotria, saw three beautiful naked woman dancers twirling in front of stone pillars that rotated slowly. Jungle scenes lit up by the moonlight, full of snakes and palm trees by the beach and lots of people I had known in my life in floating bubbles that were to the left and right of the scene, drifting up into the sky. Elephants from India embellished with vibrantly colored jhools (saddle cloth) and heavy jewellery and sparkling anklets. Detached female faces of breath-taking beauty with freckles. Waterfalls in the middle of the jungle.
 
With another session, saw barely dressed women wearing futuristic clothing and bikinis of some sort, dazzling in it's design. A spinning vortex made of blue color with closed eyes that opened up in front of me that looked like a wormhole of some sort, I travelled inside of it, and was dropped off on an island in the pacific with wooden Tikis all around the perimeter of a small culture. I saw a chalkboard full of mathematical equations and scientific discoveries drawn out. I flew like a bird for nearly a minute over what looked like Los Angeles, as I could see the homes with swimming pools and parks below me.
 
I've seen pyramids adorned with gold sheen, architecture of the past and future, Egyptian scenery, vast landscapes, medieval scenery, it goes on and on. Everything is brand new as if newly created. Very similar to the Ayahuasca visions encountered by Benny Shanon in "Antipodes of the Mind".

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#10 tregar

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Posted 04 January 2022 - 08:33 AM

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Part 8: New research: Morning glory contains 5 stimulating LSD-like drugs, soluble only in wine/alcohol, only sparingly soluble in water.
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Has the Mystery of the Eleusinian Mysteries been solved? by Ivan Valencic
hxxp://www.psychedelic-library.org/valencic.htm
 
For a visual high dose claviceps paspali (same fresh alkaloid profile as the fresh Mesoamerican Aztec/Mayan morning glory) ergot wine trip report prepared by LSD chemist Todd Skinner, reported in the literature: read Krystle Cole's 3 page report on page 2 post #32 of morning glory link above.
 
She saw "constantly rotating holographic Sanskrit or Arabic & Zodiac symbols, floating in a circle around Todd's head."
 
It just so happens that the ancient Aztec and Mayan also added the fresh or dried pulverized morning glory seeds to a drink containing alcohol, they learned this would extract all the stimulating actives from the seeds:
 
Page 515 "Encyclopedia of Psychoactive Plants" Christian Ratsch:
The fresh or dried morning glory seeds normally were added by the Aztec and Mayan to alcoholic drinks (sugarcane liquor; c. alcohol), tepache (maize beer, chicha), and balche' (Schultes 1941, 37).
 
The merck index shows that (1) elymoclavine, (2) agroclavine, (3) chanoclavine & (4) penniclavine in the seeds are best soluble in alcohol (sparingly soluble in water).
 
(5) Lysergic acid hydroxyethylamide (LSH) in the seeds only survives outside the seeds in an acidic environment (example: such as cold sherry wine which is already at ph=4). LSH decomposes in ionic conditions, neutral water (plain water), when heated, or in alkaline environments. See very bottom attached illustration of how LSH decomposes to LSA unless extracted into acidic water, wine, etc.
 
Important new 2020 receptorome binding data just came out this year that is available for LSH or Lysergic acid hydroxyethylamide found in morning glory seeds. See below:
 
hxxp://www.t3db.ca/toxins/T3D3687
 
5-ht2a, 5-ht2b, 5-ht2c, adrenal A1A, adrenal A1B, adrenal A1D, adrenal A2A, adrenal A2B & adrenal A2C
 
This is important as it shows LSH binds to just about all the adrenal receptors, while LSD only binds to one of the adrenal receptors: A2A in comparison (as far as adrenal receptors are concerned). See chart below: DMT, mescaline & psilocin all bind to many of the adrenal receptors. The adrenal receptors are implicated in the perception of aesthetics, beauty.
 
This may explain why the semi-synthetic man-made LSD has been perceived by many to have less aesthetic appreciation than the natural entheogens: LSH, mescaline, Ayahuasca (harmine + tetrahydroharmine + harmaline) with Caapi, dmt, psilocin. It's man-made quality may be more perceptable due to it's lack of significant adrenal agonism, which is prominent with the natural entheogens.
 
Example: Mescaline has a rating of 4.00 at adrenal A2C (see below), 4.00 = max = off the charts, and anyone who has ever consumed cactus knows the appreciation for beauty is "thru the roof" or "over the top".
 
Important teamwork is going on between LSH and penniclavine in the seeds, the 2 highest alkaloids. Agroclavine and penniclavine in the seeds (metabolite of agroclavine) bind to 5-ht1a, 5-ht2a, 5-ht6, 5-ht7, adrenal A2A, A2C, A2D, and most of the dopamine receptors in comparison. See "Agroclavine & Penniclavine radioligand (receptorome) data, Planta Med. 1996 Oct; 62(5): 387-92."
 
Thomas S. Ray, Psychedelics and the Human Receptorome (2010):
Breadth of Receptor Binding, 4.00=max (off the charts), 0.00=min, X.XX=receptor is hit but we don't have strength data.
LSD: 5ht1a = 3.73, LSH: = 0.00, penniclavine = X.XX, DMT: = 0.00, psilocin = 2.88, mescaline = 3.61, 5-meo-DMT: = 4.00
LSD: 5ht1b = 4.00, LSH: = 0.00, penniclavine = 0.00, DMT: = 0.00, psilocin = 2.19, mescaline = 0.00, 5-meo-DMT: = 2.41
LSD: 5ht1d = 3.70, LSH: = 0.00, penniclavine = 0.00, DMT: = 3.91, psilocin = 3.40, mescaline = 0.00, 5-meo-DMT: = 3.48
LSD: 5ht1e = 2.62, LSH: = 0.00, penniclavine = 0.00, DMT: = 3.28, psilocin = 3.03, mescaline = 3.16, 5-meo-DMT: = 1.72
LSD: 5ht2a = 3.54, LSH: = X.XX, penniclavine = X.XX, DMT: = 2.58, psilocin = 2.14, mescaline = 0.00, 5-meo-DMT: = 0.98
LSD: 5ht2b = 3.11, LSH: = X.XX, penniclavine = 0.00, DMT: = 3.91, psilocin = 4.00, mescaline = 3.97, 5-meo-DMT: = 0.69
LSD: 5ht2c = 3.11, LSH: = X.XX, penniclavine = 0.00, DMT: = 3.42, psilocin = 2.52, mescaline = 0.00, 5-meo-DMT: = 1.55
LSD: 5ht5a = 3.64, LSH: = X.XX, penniclavine = 0.00, DMT: = 3.16, psilocin = 2.83, mescaline = 0.00, 5-meo-DMT: = 1.84
LSD: -5ht6 = 3.75, LSH: = X.XX, penniclavine = X.XX, DMT: = 3.35, psilocin = 2.82, mescaline = 0.00, 5-meo-DMT: = 2.73
LSD: -5ht7 = 3.77, LSH: = 0.00, penniclavine = X.XX, DMT: = 4.00, psilocin = 2.82, mescaline = 0.00, 5-meo-DMT: = 3.69
LSD: ---D1 = 2.34, LSH: = 0.00, penniclavine = X.XX, DMT: = 3.51, psilocin = 3.37, mescaline = 0.00, 5-meo-DMT: = 2.38
LSD: -A-2A = 2.93, LSH: = X.XX, penniclavine = X.XX, DMT: = 2.75, psilocin = 1.36, mescaline = 2.92, 5-meo-DMT: = 0.00
LSD: -A-2B = 0.00, LSH: = X.XX, penniclavine = 0.00, DMT: = 3.53, psilocin = 1.57, mescaline = 0.00, 5-meo-DMT: = 0.86
LSD: -A-2C = 0.00, LSH: = X.XX, penniclavine = X.XX, DMT: = 3.53, psilocin = 1.03, mescaline = 4.00, 5-meo-DMT: = 1.57
LSD: -A-2D = 0.00, LSH: = 0.00, penniclavine = X.XX, DMT: = 0.00, psilocin = 0.00, mescaline = 0.00, 5-meo-DMT: = 0.00
LSD: -A-1A = 0.00, LSH: = X.XX, penniclavine = 0.00, DMT: = 0.00, psilocin = 0.00, mescaline = 0.00, 5-meo-DMT: = 0.00
LSD: -A-1B = 0.00, LSH: = X.XX, penniclavine = 0.00, DMT: = 0.00, psilocin = 0.00, mescaline = 0.00, 5-meo-DMT: = 0.00
LSD: -A-1D = 0.00, LSH: = X.XX, penniclavine = 0.00, DMT: = 0.00, psilocin = 0.00, mescaline = 0.00, 5-meo-DMT: = 0.00
I don't know if you remember morninglory seed from long ago? He was on another forum. Here is one of his old classic posts that makes alot of sense:
 
morningloryseed:
Unlike most alkaloids, LSA is water soluble when it is in its natural, freebase state...the way it is found in the seeds. it is a rare, exception to a rule because by simple definition, alkaloids are very alkaline or basic when in their freebase form as they normally occur in plants. Thus, they do not dissolve well into water. Most likely, many of the other ergoline akaloids probably are not water-soluble in their freebase form and thus are not extracted from the ground seed matter when a "tea" is made. or they get dissolved into the non-polar solvent used when an A/B extract is performed and they are thrown away.
 
Thus, extracts have a different mix of alkaloids and that is why the trip from A/B extracts or a "tea" of m. g. seeds feels so different than that of the whole seeds. In my vast experience with eating the seeds, and taking extracts, the trip that results is not as good. And I've taken the seeds more than any other psychedelic, except LSD and marijuana. I find them much more narcotic/sedative-like in nature and the effects are really nothing like that which I get from EATING the seeds.
 
The fact that teas or other extracts feel very different from the trip of the whole seed has also been noted by everyone I've shared m.g. seed tea with, and is a comoon thing reported in trip reports. So this is definitely not a phenomena that I am alone in feeling. Many, many, many people IM or email me with morning glory seed questions and most of them who have tried both have also noted that extracts are not as psychedelic and nowhere near as potent as eating the whole seeds.
 
The seeds do cause nausea and vomiting (as many other psychedelics like ayahuasca, mescaline, ibogaine, etc.) but a purge, I feel great. Like I said, I think the seeds are one of the best psychedelics, and I have tried quite a number of different ones.
 
Extractions such as a simple morning glory "tea", or the more complicated A/B extraction, will give you a mixture of different LSA's than those found in the whole seeds. It is the combination of all the ergoline alkaloids in the seeds that make you trip.
 
The main alkaloid is the mostly sedating LA-111, but many others (up to a dozen or so) including d-lysergic acid hydroxyethylamide (closest molecule to LSD found in nature), are known to occur in the seeds. Together, they have a synergestic efffect and produce a very different kind of experience from pure LA-111. It is (in my opinion) a great trip. One of my favorites. Of course the trip from seeds is very different from LSD. But because it is different than LSD does not mean it is not as good. I think they are both very useful. Some of my most meaningful trips have been with natural lysergic acid amides.
 
Example page from Merck on agroclavine (found in morning glory seeds):
agroclavine is soluble in ethanol, chloroform, pyridine, soluble in benzene and ether, very little water soluble.
 
From "The Alkaloids: Chemistry and Physiology", page 32:
Agroclavine is readily soluble in organic acids, agroclavine is stable to acids", wine stands as one of the sources of organic acids. Page 33 "Elymoclavine is only somewhat soluble in water" 

Peter Webster states in "Sacred Mushrooms of the Goddess, the Secrets of Eleusis" in the morning glory chapter that Chanoclavine is soluble in alcohol.

 
The hard data is lacking on whether the alkaloids in the seeds are in the freebase (like morninglory seed above describes) or in the salt form. Alkaloids such as mescaline and dmt are found in the salt form in the plant, and are readily water soluble. However, these half dozen alkaloids from morning glory are found within the tiny rubbery like embryo found within the seed.
 
To be on the safe side, extract into wine, as this will extract the alkaloids should they be in freebase form. This will give you an extract that is no different from "eating the seeds". Morninglory above is right in that the plain water extract is no where near similar to "eating the seeds" or an acidic wine extract (editor preferred).
 
(1) Hermes (the Lycaeum):
Saw strong 4D lattice-like open eye visuals and warping and melting of furniture with only 400 seeds. There are around 32 to 36 seeds to a gram. So 12 to 14 grams is 400 seeds to 500 seeds. I extract into water pre-acidified with a squirt of lemon juice. I see amazing three and seemingly four-dimensional shapes morphing and bifurcating. Often I get religious and esoteric themed visuals, like fractal cherub wings and winged eyes like those in some of Alex Grey's work. Eyes are all over everything. I see pyramids and sphinxes and Gigeresque biomechanical forms. I see amazing geometric lattice structures. I watch mathematical space-filling algorithms doing their thing, all of this with nothing more than 500 seeds.
 
(2) Nogal (the Nook):
Yes I know of someone who tried the CWE method with the Heavenly Blue variety, except with the substitution of a coffee grinder in place of a stone metate (I think that's what is called but I could be wrong), and a squirt of lemon in the water, with around 400-500 seeds. Closed and open eyed visuals were extremely breath taking. Some of the most prominent visions were of Aztec/Mayan glyphic patterns, a menacing and demonic technicolor nymph made of light who tried to seduce the viewer, and this bizare trail of energy spheres which each contained a different stylized animal form (again definately of Aztec/Mayan origin).
 
(4) Piper methysticum:
Morning Glory seeds are definitely the most euphoric psychedelic I've ever taken during the onset and the first part of the peak. Not even a strong dose of MDA could compete with the euphoria I felt from 12g of Morning Glory seeds. However, the comparison of LSA alkaloids to MDA is ridiculous. The visuals from Morning Glory seeds are quite inconsistent for me. The first time I tried them, at 9g, the visuals were very dull, but the mental and physical aspects were awesome. My second time at 12g, the visuals were beyond amazing. I got the feeling of being completely in a warp through time and visuals were flying past me and unimaginable speeds. A couple of my unexperienced friends were talking about the tracers they were seeing at the same time this was happening to me. I had to laugh. With just 6g my third time, I also had some pretty amazing visuals, though they weren't nearly as mind blowing.
 
(5) Myself, 400 black hard fresh seeds right off vine, grown in 75% miracle grow & 25% cow manure compost: extracted with 2 shots (60ml) of fresh just opened cold sherry wine with added 10mg of DL tartaric acid powder added (auction sites or *ma*on), and stirred together in the wine really well.
 
DO NOT ADD MORE THAN 10mg DL tartaric acid to the 2 shots (60ml) of sherry wine...too much DL tartaric acid can upset ph balance of the body and you will feel really bad...10mg will keep ph no lower than 3.5. The wine will go from natural ph=4 down to ph=3.5, but no lower. You will need a 1mg (0.001g) electronic scale to do this, like the AWS GPR-20 20g x 0.001g scale for example. It needs to be DL tartaric acid and not just plain L tartaric acid, The d-form salt is the form LSD is active as for example, not the L-form.
 
You crush the seeds inbetween a paper plate with ends folded in, you hammer the plate on a concrete surface, then you add the crushed seed powder to a coffee grinder, and grind it till it is nearly a dust...then you add the dust like seed powder to the 60ml of cold sherry wine in a tall 1/2 pint jar, then you let it sit in fridge for 3 hours, with shaking & stirring once per hour.
 
Then at the end of 3 hour period, you decant off the top liquid from the seed debris at the bottom....filter the sherry wine liquid thru a cotton ball in a funnel which sits in a jar, change out the cotton ball when or if it clogs, I usually have to change the cotton ball out once or twice, the top of the cotton will turn black or dark brown. The cotton ball will remove ALL the nauseating debris from the sherry wine/seed mixture. You will be left with a golden clear to light brown golden liquid, this is what you drink--no nausea as all the debris has been removed!
 
Before you consume, always remember to keep the 2 shot sherry wine extract of the morning glory seeds cold at all times (in the fridge) as acetaldehyde boils off at room temp or 69 degree F. You don't want your LSH decomposing to LSA do you? You can freeze it too if you plan to use it at a later time.
 
I saw geometric patterns on the surface of everything, with closed eyes, colored vectors spun 360 degrees while traveling from left to right across visual plane. Sounds were not only amplified & music heavenly but audio hallucinations were produced, heavy euphoria component & very strong appreciation for beauty. Remember watching Scarlett Johansson interview on a small television and melting into the seat from her beauty amidst all the breath taking geometrics. Tripped hard as hell.
 
Note: Cold sherry cooking wine is recommended as an extraction solution since it is already at ph=4 and is 18% alcohol, and is also very cheap ($5 per bottle). It can be found in the wine isle of any grocery store, and is often on sale. It also contains 10mg acetaldehyde per each shot (30ml). A $9 wine preserver canister can be bought at Amazon which contains a gas mixture of argon, carbon dioxide & other inert gases which can be sprayed into an open bottle of sherry wine before sealing cork to preserve the wine indefinitely, otherwise the acetaldehyde in the wine converts to acetic acid over time, giving the wine a vinegar taste. The wine preserver contains enough gas to last for years of sealing many bottles.
 
2016 Polish morning glory study found 3x higher amounts of LSH in MG seeds direct from grower/producer vs retail:
seeds direct from growers: 1.71 LSH to 5.08 penniclavine ratio
seeds off retail racks: 0.54 LSH to 4.75 penniclavine ratio
Immediately vacuum pack and freeze freshly picked dark hard black seeds off vine to preserve potency indefinitely.
 
Erowid report:
400 older dried seeds is similar to a little less than one hit LSD. 400 fresh off vine is like about 2 or three hits.
 
dmthead420:
Seems this does do alot more, its alot more refined, clean, less body high all mind high.. i extracted 700 riveas into 100 ml of lemon juice , 50ml water .. that sat 9hrs in the fridge(water stayed the color of lemon juice but smelled like alkaloids) i filtered and added 100ml of sherry wine and that sat 6hours..
 
A buddy and i sampled 12ml of this and the effect is way different from just eating the seeds or just a simple water extract..
 
No body feelings AT ALL, not even the normal body buzz.. just a extreme lsd like head and abstract thoughts, better sense of understanding.... Real soon i am def going to try a large dose ..I Feel GreaT...I will no longer do it any other way.....my friend says the same.
 
Norman said on 16 September 2019:
Years ago I stumbled across a simple method for dosing HBWR.
Grind the seeds and cover them with white wine, let sit in the fridge for a day or so, shaking occasionally, decant, filter and drink.
No nausea no aches no vasoconstriction.
I am now off alcohol completely so I’m thinking of an alternative method short of a full on extraction.
I’m convinced that something in the wine besides water and alcohol is what makes the trip so clean. I’ve tried twelve percent water alcohol mixes in the past and still had the nasty side effects and at the same time the trip is not as strong.
I’m thinking acetaldehyde and or tartaric acid may be involved or at least a good place to start.
Any thought on what chemically may be going on?
 
Vecktor (advanced chemist):
Tregar, you have probably rediscovered something that has long been a curiosity, for example on the now defunct blacklight site there was TLC posted of morning glory seed extract treated with methanol, acetaldehyde-methanol or with acetaldehyde-methanol-water, the extract treated with acetaldehyde-methanol showed a clear difference in the alkaloid profile, with a shift to several new non polar spots which couldn't be identified. IIRC Erhlichs was used to develop the plates so these were indole compounds.
 
69ron:
I know some of you out there are apt to believe the statements above because you've failed at making LSH and those statements above help you feel better about you're failure. Don't fall victim to that kind of crap. Try it again. Find out what you did wrong. When it works, the difference is HUGE, not a tiny difference, the experience is TOTALLY DIFFERENT. SWIM knows the effects of LSA and LSD very well. He’s used them many times. He guarantees that when the reaction works, there is NO NOTICEABLE LSA left at all in the experience. It becomes almost identical to an LSD experience at low doses. Totally different from LSA.
 
According to Albert Hofmann (the inventor of LSD), LSH is an adduct of LSA and acetaldehyde. Adducts are very simple to make. You just mix them in solution, that's all.
 
The effect of adding acetaldehyde is HUGE. SWIM cannot feel any leftover LSA when the process is done right. So, like I said, I think those guys don't know what they're talking about and I believe Hoffman does, and that LSH is an adduct of LSA and acetaldehyde and nothing more. No complex reaction is needed to make it. You just mix the two together and LSH forms. And I believe all of the LSA forms LSH, not just a small amount of it because you cannot feel any of the effects of LSA after this is done right.
 
When the conversion from LSA to LSH is complete it feels COMPLETELY DIFFERENT. The reason some people can't tell the difference is because their conversion failed. It doesn't always works, but when it does, the difference in effects are night and day. No one would ever think the effects of LSH are anything at all like LSA. It's that different.
 
fastandbulbous (chem wizard from bluelight):
Apparently N-(1-hydroxyethyl)lysergamide (LSH) is an adduct compound formed from lysergamide (lysergic acid amide, LSA/LAA, LA-111) and acetaldehyde. This hints towards the idea that isn't the most stable of compounds, but would be pretty easily formed by the combination of lysergamide (LSA) & acetaldehyde under physiological conditions (ie a way to get much more & better psychedelic activity from any lysergamide extracted from seed sources).
 
Chemist Peter Webster who spoke at the LSD symposium:
LSH is a labile adduct of ergine (LSA) and acetaldehyde.
 
Mid April: I am growing a small fence line of heavenly blue morning glory, so I will let you all know how my new dream experiences go this October or November when I pick them out of the pods once hard and black, then immediately freeze them. The seeds all sprouted only 1 week after planting the seeds in the 75% miracle grow mixed with 25% cow manure compost, both from big box home store. I dug a small 2 to 3" trench into ground, and filled it with the soil mix, planted one seed every few inches, 95% of them sprouted one week later after watering them daily. I feed them 1 tablespoon of miracle grow powder mixed into 1 gallon of water in watering can x once a month only. This will yield seeds of very high potency.
 
The application of NPK fertilizer (miracle grow) + composted cattle manure increased crop yield by 48.9% compared to NPK fertilizer alone ---> from 2017 Frontiers in Microbiology, 05 Sept 2017 "Composted Cattle Manure Increases Microbial Activity and Soil Fertility." Some users report that their plants grew three times in size once they added miracle grow soil to their existing potting soil.
 
As you can see, I used zinc #212 "screw eyes" from hardware section of big box store screwed into fence after drilling a tiny hole for each one, and strung fishing line inbetween the eyelits, this supports the vine, this is how I have grown for years. Train the vine horizontally on the fishing line if you want and once the vine reaches top of 5' fence, it can cross over top of fence and continue to grow or droop downwards on opposite side, for many extra feet of growth.
Steps in the morning glory extraction (see very bottom attached photo):
 
I would suggest doing this under low light conditions, I personally replace a lamp in room with an LED Red bulb I found at grocery store in hardware section for five dollars when normally doing this.
 
1. eight grams weighed out on folded over paper plate, then hammered in between plate on concrete with hammer.
 
2. then the hammered mush was further ground in coffee grinder.
 
3. mush sitting in one half pint tall jar. (these jars can be found in canning section of stores)
 
4. 2 oz (60ml) of cold sherry wine added to mush and transferred to fridge for 20 minutes, shook hard every 5 minutes. (Shake hard three times or every 5 minutes during the 20 minute soak)
 
5. after 20 minutes in fridge observe course debris at bottom.
 
6. after 20 minutes in fridge, then filtered thru a cotton ball in a funnel, press on cotton ball using straw when dripping stops to get all remaining light colored wine solution out.
 
7. observe wine solution dripping thru cotton ball, solution is light colored and free of nauseating to the stomach and intestines debris!
 
8. closeup of 1st cotton ball in funnel after filtration, it took out ALOT of dark colored debris that is nauseating to stomach and intestines.
 
9. closeup of first cotton ball used for filtration, super dirty black at top 1/3rd portion.
 
10. first cotton ball changed out half way thru process, as it clogged, then replaced with a 2nd cotton ball to filter out remaining liquid which was in the funnel.
 
11. The end! 1.5 oz liquid collected from starting 2.0 oz, put back into fridge until use. Heavy nutty flavor, 100 percent free of nauseating to the stomach and intestines debris. All the actives remain in solution while the debris has all been eliminated. Prepare for a very euphoric and lucid visual trip with deep insights...combines extremely well with other entheogens as well.
 
12) Wine solution when dabbed on cue tip and touched to paper plate, glows bright blue
 
13) Her, underground house DJ
 
Pics appear to be posted backwards, no matter how I re-list them, 1st photo at very right, then in sequence from right to left. Very bottom photo of screen = step #2 the coffee grinder.
 
morning glory 1.JPG
 
morning glory 2.JPG
 
morning glory 3.JPG
 
 


#11 tregar

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Posted 04 January 2022 - 08:35 AM

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part 9: 20 minute visionary visit from a dead Aztec Shaman
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This is how I got into growing morning glory, thought would share as I feel it was more a message from the Aztec Shaman, also goes to show the visual power of high dose LSD made from ergot alkaloids, this really happened.
 
Over 12 years ago, girlfriend and I both dropped 10 hits each of super old 15 year old decomposed acid given to us by a dear friend, he had stored it in between the pages of a book all that time without using a baggie, when held in front of blacklight, only around 60% of each blotter glowed, rest decomposed. It had a sick feeling for the first 2 hours, but then it worked and skyrocketed us to a higher divine plane, it was very strong.
 
She and I both saw the exact same vision for 20 minutes straight which had formed out of the shadows cast by the fake Christmas tree lights onto the wall--a 20 minute "schooling" by an ancient powerful & spiritually prominent Shaman from Aztec era --- I have never had an experience like that ever again to this day--it was a once in a lifetime opportunity.
 
The Shaman sat on a living chair made of spirit animals (birds, jaguars, otters, pumas, macaws, toucans) that morphed into other animals constantly, to the left and right of him were centaurs (half animal below, half naked female above), the great Pyramid of the Aztec capital behind him, and he showed me the rise and fall of several civilizations throughout time--and what is even more amazing--is that we both saw the exact same vision.
 
The Shaman wore a huge beautiful headdress made of feathers and the detail of the 20 minute animated vision was beyond 4k, and extremely detailed--it was also the vision in which I saw snakevines behind the centaurs, and before the Shaman left us at the end, he motioned to me with his eyes to look to the right of the living room out the window into the patio area where I had an empty garden plot--he was trying to tell me to plant entheogenic plants in the plot--that spring, summer & fall I grew morning glory in that plot on a large wide & tall wooden trellis cemented into the ground.
 
His point in showing me the rise and fall of the different civilizations was that I believe he was trying to tell me that "if humanity is to survive, the only hope is a Spiritual Solution".
 
morning glory 4.JPG

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#12 tregar

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Posted 04 January 2022 - 08:38 AM

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Concluding notes on morning glory seeds
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Below (1-6) from 1975 paper "Extraction and Identification of Clavine and Lysergic acid alkaloids from morning glory", see end of post #8 at top for latest "2016 attached 12 page paper", valuable morning glory study on LSH & other alkaloid levels found in morning glory from 3 different vendors, all levels very similar, collected from heavenly blue mg from 3 different regions located far apart.
 
The attached 2016 Polish morning glory study at end of post #8 (is somewhat similar to the 1975 study) except it shows penniclavine and LSH to be the 2 highest alkaloids, with the other alkaloids filling in the lower percentage.
 
hxxps://kb.osu.edu/bitstream/handle/1811/22310/V075N4_198.pdf?sequence=1
 
1) elymoclavine = approx 17% of heavenly blue mg = 1957 paper from Yui Takeo showed that when animals were injected with elymoclavine, that they were stimulated MORE than when they were given LSD.
 
2) agroclavine = approx 25% of heavenly blue mg = 1957 paper from Yui Takeo showed than when animals were injected with agroclavine, that they were stimulated MORE than when they were given LSD.
 
3) chanoclavine = approx 7% of heavenly blue mg = 1957 paper from Yui Takeo showed that when animals were injected with chanoclavine, that they were stimulated just as much as when given LSD.
 
4) penniclavine = approx 25% plus of the heavenly blue mg = 1957 paper from Yui Takeo showed that when animals were injected with penniclavine, that they were stimulated just as much as when given LSD.
 
5) D-Lysergic acid hydroxyethylamide (LSH) = approx 25% plus of the heavenly blue mg. If the seeds are not frozen & stored properly, then over time LSH decomposes to LSA (Lysergic acid amide). So the seeds may contain a makeup of 1/2 LSH to 1/2 LSA a long while later, like retail rack seeds as the LSH decomposes over time.
 
6) Ergometrine = approx 5% of the heavenly blue mg.
 
From the 1957 paper:
All members of the excitor group produced in all test animals a syndrome of central sympathetic excitation and elicited a stimulation of spontaneous activity. In this group, elymoclavine, was the most potent stimulant and next come agroclavine, triseclavine, penniclavine, and LSD which are almost equipotent, as judged by the degree of symptoms exhibited in the same dose. The arousal effect of elymoclavine or agroclavine on reserpine-sedation was superior to that of LSD.
 
Animal experiments have shown that elymoclavine, lysergol, LSD and several other ergot alkaloids such as agroclavine, triseclavine, penniclavine, lysergine and lysergene have excitory effects on the central nervous system (Note 1: Yui & Takeo, 1957) as well as lysergic acid hydroxyethylamide (LSH) which also excites the central nervous system in animals (Note 2: Glasser, 1961).
 
The effects of agroclavine are similar to those of elymoclavine and LSD on rabbits (Yui & Takeo, 1957), indicating that the effect of agroclavine may well be psychoactive in humans as well. It also seems likely that agroclavine, triseclavine, penniclavine, lysergine and lysergene and lysergic acid hydroxyethylamide (LSH) will be psychoactive in humans.
 
LSH = D-Lysergic acid hydroxyethylamide in the seeds, we know it is similar to LAE-32 in TIHKAL, in which human experiments were done, at 1.5mg it was stimulating & "LSD like".
 
Glasser in 1961 noticed animals also became stimulated when injected with LSH. Dr. Glasser said some of the mice even stood on their hine legs and pressed on the noses of the mice in front of them, very peculiar.
 
Animal tests all point to LSH being an active psychedelic and it is indeed the closest thing to LSD found in nature, far closer than d-ergine. Owsley claims Hoffman himself told him that LAOH is very LSD-like.
 
It was Gröger who first discovered LSH in the seeds, published in his 1963 paper "Über das Vorkommen von Ergolinderivaten in Ipomoea-Arten". Later also Hofmann then extracted it from the seeds. It probably was in 1967, as Heim wrote in his work from August 1967 that Hofmann said he recently extracted it from the seeds (personal communication, as they knew each other very well).
 
LSD----------------------------------------CH2CH3-----CH2CH3.....chemical formula (C20 H25 N3 0)
 
LAE-32-----------------------------------------H------CH2CH3.....chemical formula (C18 H21 N3 0)
 
d-lysergic acid hydroxyethylamide-----------H---------CHOHCH3....chemical formula (C18 H21 N3 02)
 
Penniclavine-----------------------------------------------------chemical formula (C16 H18 N2 O2)
 
Notes:
(1) The above experiments with mice, rabbits, cats and dogs who were injected with elymoclavine, agroclavine, chanoclavine alkaloids from morning glory can be found in "Neuropharmacological studies on a new series of ergot alkaloids" "Elymoclavine as a potent analeptic on reserpine-sedation" by tohoru Yui and Yuji Takeo, Hyg 911/LSD 494, Jap. J. Pharmacol. 7, 157 (1957). Jap. J. Pharmacol 7, 157-161 (1957).
 
(2) LSH experiments on animals: A. Glasser, Nature 189, 313 (1961)
 
(3) This is the paper that shows the alkaloid content of HBWR is vastly different from the alkaloid content of morning glory: Paulke A, Kremer C, Wunder C, Wurglics M, Schubert-Zsilavecz M, Toennes SW. Identification of legal highs—ergot alkaloid patterns in two Argyreia nervosa products. Forensic Sci Int. 2014;242:62–71.
 
No high levels of stimulating LSH, agroclavine, elymoclavine, chanoclavine, penniclavine found in HBWR seeds, only in morning glory seeds. A 2014 forensics paper from Paulke found no LSH in HBWR seeds, but only found LSA & iso-LSA (83-84%) & ergometrine (10-17%) & rest minimal: lysergol, elymoclavine & chanoclavine.
 
We know that MG has centuries of Shamanic use, while HBWR has no history of Shamanic use. HBWR only has history of medicinal use.
 
Sandgrease:
HBWR has more of a sedative effect compared to MG.
 
Nogal:
HBWR is more body related while MG seeds have effects more similar to LSD.
 
4) Aum_Shanti, 2019, "In fresher seeds there's mainly LSH (in relation to LSA). Only in old seeds, the LSA is dominant. This is because the fungi on the plant can only biosynthesize LSH (not LSA), and LSA is then a decomposition product of LSH over time. The fungi on the vines biosynthesize:
 
from tryptophan-->chanoclavine-->agroclavine-->elymoclavine-->lysergic acid-->ergometrine-->LSH, which then decomposes over time into LSA."
 
(5) Psychotomimetics of the Convolvulaceae pg 93: "This particular plant seems to have been more important to the Aztecs in divinity then Peyotl or Teonanacatl, two of their other classical sacred plants."
 
(6) Jonathan Ott "Pharmacotheon": "Ololiuhqui was far more prominent as an entheogen here in Mesoamerica than those mushrooms; the mushrooms are mentioned only here and there by a few competent chroniclers; yet almost an entire book was devoted to denouncing mainly the ololiuhqui idolatry. The annals of the Inquisition contain many times more autos de fe for ololiuhqui than for mushrooms."
 
(7) 2016 Polish morning glory study which finds 3x higher amounts of LSH in fresher MG seeds direct from grower/producer vs retail: hxxps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830885/ LSA is a decomposition product of LSH over time (see attached pics from study).
 
2016 Polish MG study:
Alkaloids abundance in all 3 HB cultivars is comparable, with most significant difference for LSH (Lysergic acid hydroxyethylamide), which varies from 0.54 to 1.71 compound to IS ratio.
 
As has been demonstrated in this study, LSH is a labile compound, and therefore the variances in its concentration may be due to different age and storage conditions of the seeds rather than difference in plant metabolism. Indeed, seeds IT-HB2, which express highest concentration of LSH, were bought directly from the producer, whereas seeds IP-HB1 were purchased in retail stores.
 
[8] Researchers showed in 1961 that Claviceps paspali produces high amounts of LSH in culture: "Production of a new lysergic acid derivative (LSH or Lysergic acid hydroxyethylamide) by a strain of Claviceps paspali, Stevens & Hall".
 
Possible likely entheogen candidate used to serve hundreds of initiates at Eleusis in ancient Greece: this is where the Eleusian Mysteries were held, at the Eleusis Telesterion (initiation Hall for initiates...all men, women & slaves were invited) in ancient Greece.
 
Chemist Peter Webster wrote that fresh Greek claviceps paspali infected paspalum grass which grows adjacent to Eleusis in the famous Rarian Plane contains the exact same alkaloids as found in the fresh Aztec & Mayan morning glory. Albert Hofmann wrote that Claviceps paspali due to it's similar makeup to the Mexican morning glory could also have been the likely entheogen used at Eleusis to serve hundreds of people.
 
(9) Krystle Cole from the book "Lysergic":
Quote:
"Isn't Ergot what Socrates used to take at Eleusis?" I thought it was kind of cool to be taking something that the founders of our democracy used to take, but that our current democracy has made illegal.
 
LSD chemist Todd Skinner replied "Yes". Todd had prepared 6 jugs of ergot wine and stored them for many years.
 
Krystle Cole's "ergot wine" experience (several pages long) in the book "Lysergic", reported that she saw constantly rotating holographic Sanskrit or Arabic & Zodiac symbols, floating in a circle around Todd's head.
 
(10) sample morning glory wine trip report from Erowid: Morning Glory & Alcohol by Psychopsilocybin:
hxxps://erowid.org/experiences/exp.php?ID=95057
 
I would only note that she or he should have most likely extracted the seeds from the start immediately into the wine instead of extracting into the water first...then adding to wine later, as this will cause the LSH to first decompose to LSA in neutral water or water that is not acidic.
ava


#13 tregar

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Posted 04 January 2022 - 08:41 AM

------------------------------------------------------------------
Part 10: One way to make pure tetrahydroharmine
-----------------------------------------------------------------
 
Once you get to the end of your rue extraction, where you put your rue hcl in water and precipitate the harmine from the harmaline, you want to slowly bring the ph of the water up to exactly 7.0 with drops of 10% ammonia (from hardware store, the industrial janitorial version)...at 7.0 only the harmine will fall out, collect over vacuum filter...then raise ph to 7.5 or 8.0 (your preference) and collect a small middle fraction, which you will want to set aside as it is a mix of some harmaline with some harmine...keep this fraction to add back in the future when you do another rue extract...now collect the 3rd fraction, which is the harmaline only at ph = 7.5 or 8.0 and above.
 
Details: I dissolve the rue hcl extract into water on a stir mantel, and as the stir mantel spins....add drops of 10% ammonia to precipitate only the harmine 1st, then a very small middle fraction (harmine + harmaline), then a final fraction which is only harmaline. I prefer using 10% ammonia from hardware store (janitorial). Super good PH meter: Apera Instruments ph20 ph meter.
 
Now once you have your harmaline freebase...
 
1) place 10.5 grams of harmaline in a 1 liter pyrex cup style glass
2) add 900ml vinegar
3) add 40g zinc dust (from pyrotechnic places) in the pyrex glass too, use 40g zinc dust per each 10.5 grams of harmaline. You will see tiny hydrogen bubbles rise to the surface.
5) place beaker solution on a magnetic stirrer with stir rod and spin entire solution slowly
6) spin for 1.5 hour, the solution will turn from green to a transparent like color after 1.5 hour, use end of cotton q tip to place in solution and dab on paper plate in front of blacklight, it will now glow blue when transition is done...
 
7) once done with spin, let the solution sit for 1 hour, most (99%) of the zinc dust will settle to bottom, then filter solution over a #101 9cm filter disc fitted to a vacuum flask with vacuum trap in series with your vacuum pump, this will give you a transparent golden color liquid, use this solution for next step.
 
Throw away the zinc dust you just collected on filter disc (be careful, don't throw zinc on top aluminum foil in garbage or it will smoke due to hydrogen loaded zinc, best to put used zinc in a baggie with water to keep it moist, keep away from aluminum).
 
The pump/vacuum filter flask & filter disc will remove 100% of any zinc dust. so in other words, filter pyrex beaker solution (takes out the zinc dust) over a #101 9cm filter disc fitted inside a vacuum filtration flask hooked up to a vacuum pump, with a small vacuum trap in series, in-between the filtration flask and the pump. A good pump is JB platinum DV-142N 5 CFM heavy duty vacuum pump.
 
Cool you are left with a 100% clear transparent with just a touch of golden very light yellow color with no zinc dust at all...now add (80ml of 10% janitorial ammonia per 2g of harmaline)...so this means add 400ml of the 10% ammonia to your solution...you will immediately see the thh crash out of solution as a white powder, place mason jar in fridge for 3 hours, the crystals will all be seen at bottom of mason jar.
 
9) you will collect 7.5 grams of pure white THH freebase on the filter disc sitting in your vacuum filtration flask once you pour fridge cold solution over a #101 9cm filter disc in your vacuumm pump, rinse THH with some cold water. put filter disc of thh in a pyrex tray, scrape off and dry under fan...pure white.
 
10) always this will happen: exactly 75% is the yield, as I don't know why this is so...but it's a great yield still. Even in TIHKAL, the yield was similar, right at 75% as well.
 
11) The more zinc you use, the faster the reaction progresses, so 35 to 40g zinc means the reaction is finished by 1.5 hour.
 
I've looked at the #101 filter after filtration, hardly anything at all on it, truly only 1% of the zinc dust remains to be filtered after sitting for 1 hour.
 
If you don't have a vacuum pump/filtration setup: Personally, I believe the cotton ball in a funnel to be one of the greatest inventions of all time--and think it would work just fine for filtering out the remaining 1% zinc dust, remember 99% of the zinc dust falls to the bottom already after sitting for 1 hour after the spin mantel is turned off. What you are filtering is actually the 1% of zinc dust from the very bottom after sitting that get's kicked up back into the solution as you are decanting it off.
 
p.s. I also saw an episode of "Ancient Aliens" in which they discovered remnants of zinc dust inside one of the chambers, and they believe the Egyptians were making hydrogen gas using zinc and vinegar, speculating that the great pyramid was some sort of power generating device.
 
12) This THH at 300mg is extremely visual, she's an isomer of a hormone like substance made in the brain naturally. With eyes closed for several hours are seen endless slow and high speed motion movies of nature, architecture, culture, history, the future, way beyond LSD or mescaline visuals...very realistic, mind-blowing...and with open eyes, beauty is extreme (over the top) and there is spiritual joy....this is the best psychedelic secret kept under wraps...because hardly anyone has used it over 100mg.
 
Combine 250mg THH orally (take 45 minutes before) with sublingual 60mg of DMT complexed to 470mg HPBCD, add 10 drops boiling water, mash on a spoon hard back and forth for 2 minutes using the end of another spoon, mash or knead it all hard together using your muscles, grab off spoon using bottom side of tongue (it will all adhere) and hold for 12 to 15 minutes along with 35mg sublingual harmine freebase at the exact same time under tongue...
 
...22 minutes in you will experience profound beauty with open eyes, heavy CEV visions of spinning geometrics, actual temples, and ancient architecture, never ending breathtaking immaculate visions...pupils very dilated, music sounds incredible. 90 minutes long. 300mg THH is where the visions really are seen well, if you are not used to it, there is some slight dizziness at this dosage for a short period of time, but none at 250mg. The DMT really adds to the visions as well & brightens/colorizes them, incredible combination, just like in Ayahuasca. You can re-dose more HPBCD DMT every 1.5 hour x two more times.
 
Pic1: One way to make tetrahydroharmine
 
Pic2: Dissolve your rue hcl extract into warm 115 degree F water so it all dissolves, drop in two high precision PH meters, start the spin mantel, and add drops of 10% hardware store ammonia until you reach ph=7 when the harmine only will fall out, ph 7.1 to ph 7.9 = small middle fraction of harmaline mixed with harmine, put away and save for a rainy day when doing another extraction to add back in, ph 8.0 and above = all the harmaline only.
 
THH 1.JPG
 
THH 2.JPG

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#14 tregar

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Posted 04 January 2022 - 08:43 AM

HPBCD additional pics

 

HPBCD 3.JPG

 

HPBCD solubility.JPG

 

HPBCD 4.JPG


Edited by tregar, 04 January 2022 - 10:25 AM.


#15 tregar

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Posted 04 January 2022 - 08:45 AM

---------------------------------------------------------------------------------------------------------------
part 11: From the archives of DMT world: How to easily extract 2.3g DMT from 170g bark using a 2 liter Erlenmeyer flask
---------------------------------------------------------------------------------------------------------------
 
From the archives of DMT world, pre-runner to DMT Nexus forum, chemist tek:
Super easy instructions for 2.3g DMT from 170g bark all in one day using a 2 Liter erlenmeyer flask and long glass pipette with rubber bulb on end for the pulls (zero drip).
 
Chemist tek: which yields 2.3g DMT from 170 gram powdered bark: all 4 pulls are using 90ml naptha on 150g powdered bark mixed into 1.8 liter lye water (1.5 x 150g bark = use 225g lye dissolved into the 1.8 liter 150 degree hot water.) Just heat up 1.8 liter of water in a big pyrex pot on stove and use thermometer to pull if off when it reads 150 degree F.
 
Slowly sprinkle lye using safety goggles and long chemical resistant gloves that go up each arm, and stand back as far as possible...(the hot water will fizz but not boil up) into your pyrex pot of hot water. After each sprinkle, stir the water a bit with a super long metal spoon. It will "growl" a bit as it fizzes, but this way it dissolves very fast into already hot water.
 
Pour this lye water into your 2 Liter erlenmeyer flask using a large automotive funnel. Add 170 grams of finely powdered bark, and use a long chopstick or similar to mix it all together.
 
Use (.6 x 150g bark = 90ml naptha pull for each of the 4 pulls). An erlenmeyer flask makes it easy to do pulls using a long glass pipette, as the top of flask is tapered, so all the naptha collects at the top for easy pull.
 
Use an electronic thermometer to check the temp of the Lye water bark mix, when the lye water cools down from 150 degree F to around 120 degree F, then it's time to add your 90ml of naptha, make sure your 2L flask is sitting on a mitten or similar...this makes it easy to swirl your flask to mix the contents, make sure you are using the proper rubber stopper number 9.5 to seal the top of your flask once you turn it upside down then right side up to mix the contents as well.
 
Do a combination of swirling and a couple of upside down then right side up turns of the 2L flask, then once right side up, let the rubber stopper out, and let the stopper just barely sit in the flask (not tight), so gasses can exit. After 1/2 hour, all the 90ml of naptha will migrate & collect at the top of the tapered erlenmeyer flask...use your long glass pipette to collect the naptha, that's it! very easy, no mess, and the tapered erlenmeyer flask and glass pipette with round rubber plunger at the end makes it easy to collect the naptha at the top without collecting any lye water by accident, based on chemist tek.
 
No need to do a sodium carbonate clean on it, it's plenty clean already.
 
More notes:
 
Erlenmeyer flask tapers towards the top, makes extractions easier using a glass pipette, as all the naptha collects in a narrow band tapered area near the top.
 
Yield from 170g finely powdered bark using a 2 Liter erlenmeyer flask with 9.5 number stopper:
 
1st pull far left, dish + coffee filter = 1668mg
2nd pull in middle, dish + coffee filter = 517mg
3rd pull to far right = 155mg
4rth pull close to nothing
3 pulls get majority of it all (95%)
total = 2340mg
 
1) For 170g bark, use 1.8 Liter 150 degree water, when water, lye and bark all dissolved, liquid will all come up exactly to the 2,000 ml line on the flask.
2) 170g bark x 1.5 = use 255 grams lye
3) use 3 x 90ml naptha pulls, each 90ml naptha addition will rise 1.5" or so above 2L line on flask for easy collection using a long glass pipette.
4) allow 30 minutes for each naptha pull to rise to top for collection, this will ensure it all rises. Do pulls one after another, around 1.5 hour beginning to end, then you are done with 3 pulls.
 
The pre-heated water with mixed lye keeps liquid/naptha warm...keep a 60 watt lamp bulb with reflector close or pointed to back of flask the entire time, so each of 3 pulls are around 125 degree F when measured with electronic thermometer.
 
It's very important to let your dishes sit undisturbed for a long while, dishes sit in freezer for 12 hours during day (11am till 11pm), then overnight for 8 hours.

 

Extraction pic attached from DMT world archives.
 
extract 1.JPG


#16 tregar

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Posted 04 January 2022 - 08:49 AM

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Part 12: Out of print writings on the Divine Plant of the Incas, strong euphoria & psychedelic visions from coca leaf tea bags.
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Cocaethylene (coca leaf tea bags soaked in wine, the orally active & potent ingredient formed in the liver from cocaine + ethanol in the 1860's "Vin Mariani" wine popular with both Popes, Thomas Edison and scores of other famous people) increases the levels of serotonergic, noradrenergic, and dopaminergic neurotransmission in the brain by inhibiting the action of the serotonin transporter, norepinephrine transporter, and dopamine transporter. These pharmacological properties make cocaethylene a serotonin-norepinephrine-dopamine reuptake inhibitor [SNDRI; also known as a "triple reuptake inhibitor"].
 
Cocaethylene has a higher affinity for the dopamine transporter than does cocaine, but has a lower affinity for the serotonin and norepinephrine transporters. In McCance-Katz et alia's 1993 study cocaethylene "produced greater subjective ratings of 'High' in comparison with administration of cocaine or alcohol alone."
 
Years ago, put 6 teabags in my mouth, adding some baking soda, activated the tea, painted an entire barn one afternoon, endless effortless energy, so long as kept adding some bags into cheeks every hour or so. Only thing is it makes the teeth turn green color, not attractive in western society.
 
Yes, you can add coca leaf tea bags to a couple ounces of high alcohol wine (at least 18%) like sherry wine, let it soak a while, drink wine, can get very high, nice very strong euphoria. You can squeeze 2 to 3 bags into 2 ounces of wine, very pleasant strong euphoria for at least 1.5 hour. This coca tea wine can be combined with other psychedelics for an incredibly euphoric psychedelic trip. Love
 
Coca tea is served at all the restaurants in Bolivia, very common there. I never got much of anything out of the 6 bag tea, but the bags placed in cheek with baking soda works quite well for clean energy and coca tea contains more vitamins and minerals than most anything else.
 
There is a quote in the "coca leaf and cocaine papers" by Andrews and Solomon where the neurologist Paola Mantegazza way back when used to put amounts of coca leaf (coca leaf tea bags will substitute) in his cheeks with a pinch of baking soda. He has a chapter in the book, he got so freaking high, even to the point of psychedelic visions:
 
Page 38 "coca experiences" by Paola Mantegazza (1859) from "the coca leaf and cocaine papers":
An hour later I was sufficiently calm to write these words in a steady hand" "God is unjust because he made man incapable of sustaining the effect of coca all life long. I would rather have a life span of ten years with coca than one of 100000...(and here I had insered a line of zeros) centuries without coca.
 
Bad ass out of print book, 371 pages, all about the Divine plant of the Incas.
 
You really have to read the chapter by Paola Mantegazza (page 38-43) on his coca tea in the cheek experiences, mind blowing. He took many drachm amounts of coca leaf and got high as all get out.
 
Page 40:
The maximum dose of coca I have ever chewed is eighteen drachms in a day, taking the last ten in the evening, one after the other. It was the only time that I fully experienced the delirium of coca intoxication, and I must confess that I found this pleasure by far superior to all other physical sensations previously known to me.
 
Half an hour later I chewed two more drachms of the leaf, and my pulse rate increased immediately to 120. It was then that I started to have a sensation of extraordinary happiness; I dragged my feet as I walked and I distinctly felt my heart beating. I could not write except with great difficulty.
 
By the end of the following 2 hours I felt extremely happy. My pulse rate remained at 120; I lay in the happiest sensation of a full and active life. A quarter of an hour after having taken the last two drachms I begun to shut my eyes involuntarily and the most splended and unexpected phantasmagoria started to flit before my eyes.
 
Page 42, psychedelic visions from cheeks full of coca leaf with pinch of baking soda to activate, 3.8 gram = 1 drachme:
On another occasion, having chewed coca leaf after dinner, I began to hallucinate after the sixth drachme. This effect lasted for over 3 hours, in the course of which I chewed two more drachms. Although I was immersed in a state of indescribable bliss, my consciousness was unimpaired and I was able to record some of the bizarre images that passed before my eyes swift as lightning. Here are a few; it should be kept in mind that for each one I managed to transfer to paper...I missed ten on account of their rapid succession:
 
A cave of lace through the entrance of which can be seen, toward the back, a golden tortoise seated on a throne made of soap...
 
A battalion of steel pens fighting against an army of corkscrews...
 
Lightning, consisting of glass threads, piercing a whole Parmesan cheese crowned with ivy and berries...
 
A saffron inkwell from which is born an emerald mushrooms studded with rose fruits...
 
A ladder made of blotting paper lined with rattlesnakes from which several red rabbits with green ears come jumping down...
 
Plucked Chinese flowers with burning silver stamens...
 
Looms made of matchsticks upon which cicadas are weaving pine trees made of suphur...
 
On the day following this experiment I felt more vigorous than usual, in spite of the fact that the nigh I had only one hour's sleep.
 

 

 

Remember when coca tea leaf boxes of 100 per box were sold on *mazon for cheap, along with 1 foot sections of bridgesii cactus, now you can't even buy any entheogens on *bay, only t-shirts or jewelry portraying the entheogen, just like Western man to turn it all into materialism.
 
Natural entheogens have been squashed by the pharmaceutical companies and teams of lawyers on all the sites while the Earth continues it's acceleration headfirst into climate crisis.
 
You can still order coca tea from Peru, it still has all the alkaloids, just have to use crypto. I still see some places carry a box of 100 for less than price of two movie tickets. Delisse is good stuff, it has all the alkaloids, use to buy it many years ago.
 
Wouldn't it be nice if we could let Peru and Bolivia sell the coca tea boxes in the states to legitimately make some money for their struggling economies?
 
William Martindale, author of "The Extra Pharmacopoeia" seriously suggested that Englishman should drink coca tea rather than tea.
 
Not a big fan of alcohol, so would stuff as many tea bags into a few oz of wine as could fit, let soak in fridge many hours, strain, drink, strong euphoric stuff for at least 1.5 hour, only used a few times many years ago, but remember those times as clear as a bell.
 
The median half-life of cocaethylene was 144.3 minutes (2.4 hours) whereas the median half-life of cocaine was 96.7 minutes (1.6 hours).
 
Cocaethylene is orally potent at lower doses than cocaine (not orally potent) and was discovered to form in the liver in 1994. But the book mentioned above also lists a hosts of other active alkaloids in the coca leaf. There is a synergistic effect.
 
How to make the highly euphoric coca leaf tea wine, last 2 pages of 2nd book, 5 to 6mg cocaine per tea bag soaked in wine converts to orally active more potent cocaethylene. More euphoric than cocaine and lasts x 1.5 times as long. (1.5 hour very strong euphoria).
 
Pic1: Last 2 pages: attached out of print writings on how to make euphoric psychedelic coca wine, soak two coca leaf tea bags per each 1oz of wine, then drink wine.
 
Pic2: Feminine spirit, meditation at the ruins.
 
coca1.JPG


#17 tregar

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Posted 04 January 2022 - 08:50 AM

------------------------------------------------------------
Part 13: THH + mushrooms report from friend
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Just wanted to let you know that I finally tried 3 grams of cubensis with 180 mg of THH, and all I can say is WOW! Intense and beautiful like I've never had before, with a definite DMT edge to it.
 
I've always been a hard-head, needing 4.5+ grams to get anywhere interesting. I've done up to 9 grams, and never got near this intensity.
 
Just wanted to thank you for the tip. This is the way for me to go form now on.
I look forward to combining THH with DMT.
 
All the best, and take care.


#18 tregar

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Posted 04 January 2022 - 08:54 AM

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Part 14: Tetrahydroharmine (THH) + 1-acetaldehyde LSD (identical to ALD-52) trip reports
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If you don't have LSD, then just substitute a 2oz fresh fridge cold just opened sherry wine extract of morning glory as explained earlier in this paper.
 
Have used this combination x 3 times, every 2 weeks, ranks up there with the most profound entheogenic experiences I have ever experienced, just as strong, long-lasting, visual, super neon-colorful & music-enhancing as two feet super fat bridgesii cactus, and I've drank cactus tea over 200 times now.
 
Used to spend hundred of dollars a year drinking cactus tea all year long, at least twice a month, this method is an identical replacement in my humble opinion, and lasts all evening with super long afterglow, very similar to 600+ mg of mescaline, and dirt cheap compared to the rare and very expensive cactus which is only becoming more scarce as time goes on due to demand and less growers.
 
This is the infinitely beautiful combination of tetrahydroharmine or THH with 1-acetaldehyde LSD (identical to ALD-52).
 
THH has numerous similarities to mescaline, best kept secret in the psychedelic world, it combines extremely well with other psychedelics and brings out there essence.
 
THH can be combined with other "oral psychedelics".
 
THH has numerous similarities to mescaline, not only does it block serotonin like mescaline, LSD & shrooms, but it agonizes all 3 adrenal receptors just like mescaline, which are associated with beauty & aesthetics appreciation, beauty enhancement is "over the top" when THH is included.
 
Actresses on TV will look like dazzling glowing super-colorful cartoon caricatures of themselves (just like with high dose cactus tea) only if you include the THH. Researchers have called THH the "tryptamine of the beta-carboline world" and rightly so.
 
Music will sound bad-ass incredible (way beyond LSD enhancement) only if you include from 150mg to 300mg oral THH with your 1-acetaldehyde LSD. Take them both orally at the same time.
 
300mg THH + 250ug 1-acetaldehyde LSD report (2oz fresh sherry wine morning glory extract can substitute as well):
 
One month ago combined 300mg of THH or tetrahydroharmine with 250mcg of acid paper that had been soaked in 1 shot of fresh just opened cold sherry wine for 3 hours in the fridge with hand stirring once an hour in the fridge for 30 seconds, to help theoretically or hypothetically convert the LSD to the more neon-colorful & visual and head-space gentle (zero-anxiety but still super-deep head space) 1-acetaldehyde LSD or nearly identical to ALD-52 by adduction of the acetaldehyde from the sherry wine to the NH bottom indole position on the LSD (don't try this at home unless you are really advanced, and sure you have very pure THH) and had closed eye bright colored teaching visions all the way from 8pm till midnight.
 
Much more powerful than LSD visions alone, these were brightly colored Ayahuasca visions. One of the sequence of visions were of a variety of stone carvings with very elaborate artwork and a beautiful woman who stretched out her hand to me to show me magic.
 
I would need a tape recorder going for hours to talk into in order to record the hundreds of non-stop CEV animated and static colored visions.
 
Then at midnight took another 100mg of THH, it brought the visions all back until 4am in the morning! Non-stop hundreds of Ayahuasca visions for hours and hours, I was completely blown away, and listening to music on my headphones, which sounded as if I had taken a high dose cactus tea, very remarkably enhanced, just Heavenly.
 
Where just LSD and psilocybin alone heighten and clarify the sense of hearing, the combo of 300mg THH + 250ug 1-acetaldehyde LSD produces auditory hallucinations, heightening the hearing sense but also causing sounds to be quite different than normal. Music sounds as if you were an extraterrestrial being, immersing yourself in new sensory phenomena for the first time. Each instrument stands out on it's own, every track heard as if experienced for the very first time.
 
This combo experience is much more visual than mushrooms or acid. This is very much like the combo of mescaline with a more visual, colorful & stronger version of LSD (1-acetaldehyde LSD). It's like a ZERO anxiety LSD with a very deep head space. 
 
The combo experience makes the music sound just as good as using two feet fat bridgesii cactus tea. As I was watching a movie, all the actresses looked like glowing, dazzling, super beautiful-colorful cartoon caricatures of themselves, and the euphoria way over the top...all the colors in the movie poured over into the room and onto the walls, forming alternating neon colors on all the walls, incredibly beautiful. I saw colors on the wall that did not belong on this earth such as neon purple-yellow! I still can't stop thinking about this weeks later, the most beautiful colors I have ever seen.
 
Please note: all beginners only use around 150mg to 200mg THH which is what is found average in 1 cup of Ayahuasca tea, only advanced members of the UDV, Santo Daime, Shuar Indian and people like myself drink 2 cups of Ayahausca tea for the evening, which then contains around 300mg THH average.


#19 tregar

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Posted 04 January 2022 - 08:59 AM

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Part 15: How to theoretically form 1-acetaldehyde LSD (similar to ALD-52 or 1-acetyl LSD, Orange Sunshine) from LSD hits
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1-acetaldehyde LSD (nearly identical to ALD-52) will theoretically form when you drop hits of LSD into 1 shot of fridge cold just opened sherry wine, stir once an hour for 3 hours, keep in fridge at all times, as acetaldehyde boils off at room temp or 69 degree F, then consume...all explained below:
 
Sherry wine is high in acetaldehyde (10mg per 30ml or shot glass). This serves as an advantage...why is this possibly important?
hxxps://www.ncbi.nlm.nih.gov/pmc/articles/PMC49935/
 
Page 8441:
Reaction of Indole with Acetaldehyde: A 0.2% solution of indole in equal amounts of water, ethanol, and acetaldehyde formed a product with 60% yield after 1 hour of reaction at ambient temperature. Omitting the ethanol (50% acetaldehyde in water mixture) had no effect.
 
Decreasing the concentration of acetaldehyde to 0.1% increased the reaction rate and percent yield of product.
 
See pic of the researcher's indole + acetaldehyde adduct product formed before (page 8439) and after (page 8441).
 
The researchers achieved a new product with or without the use of ethanol, it made no difference, you only need water acidified to around ph=4 and around a 0.1% acetaldehyde solution, and around a 3 hour soak time for 100% conversion.
 
Sherry wine fits the bill perfectly with it's high acetaldehyde content, and low ph, which is already at ph=4, just like the study calls for. The researchers stated "the lower the PH, the faster the reaction (indole adduct formation at the NH group)." It contains the perfect amount of acetaldehyde as well, in an alcoholic medium no less.
 
It is quite possible that 1-acetaldehyde LSH and 1-acetaldehyde penniclavine produce stronger visual trips with zero anxiety. This has been my experience with the seed solution and also my experience when converting 3 x 100ug blotters of LSD to 1-acetaldehyde LSD (have done this over 10 times already spaced at least two weeks apart during the past two years), also confirmed recently by Namaste at the Shroomery to work for him as well, now his preferred method of consuming LSD as well.
 
Once you know your morning glory seeds are potent, you could also throw in a blotter or more of LSD into the sherry wine/morning glory seed solution soaking in the fridge for 3 hours, not only will this convert the LSD to the more visual, colorful and anxiety free 1-acetaldehyde LSD but it can result in a trip way beyond normal LSD. Example below:
 
Dragonrider:
I have also experimented with morning glory seeds a lot. A couple of times the seeds came very close to LSD. I have combined morning glory seeds with other psychedelics. On a few occasions, they boosted the effects of psychedelics enormously and very few seeds where actually needed to create this effect.
 
Once a mere 30 seeds were enough to cause an overwhelming OBE on LSD, paired with the most insane visuals and a defragmentation of the mind like i have never experienced ever since. I am convinced that there is a substance in fresh morning glories, and maybe it is LSH or penniclavine, that modulates receptors that are being activated by psychedelics in such a way that it can boost the effects of other psychedelics.
 
How 1-acetaldehyde LSD is different from LSD:
 
1) You know how acid has that sudden drop off then you are back to sobriety? Instead, this lasts longer than acid and has a warm gentle transition back over a longer period. The come up is also gradual and smooth similar to cactus.
 
2) 1-acetaldehyde LSD is way more colorful than acid, similar to mescaline.
 
3) 1-acetaldehyde LSD does not have the "visual choppiness" of acid, but is flowing in the visuals.
 
4) LSD produces tracers with multiples of shadows of the hand, this produces not only tracers, but colored fractals and mosaics inside the tracers.
 
5) LSD produces "colored specs that flow in front of everything", this produces instead "fine colored rainbow reflections" that surround everything.
 
6) Music sounds good on acid, but music sounds great on this, like a whole nother world, similar to mescaline.
 
7) With 1-acetaldehyde LSD, everything seems alive and magical. Patterns & neon colors form everywhere, the shifting of textures is magical. You can lose yourself easily as the visuals seem to drag your focus in without any effort. As a result, ego death is basically spontaneous.
 
8] Sometimes LSD causes wandering thoughts & can seem abrasively analytical but with 1-acetaldehyde LSD there is no wandering thoughts, no tenseness or anxiety like with acid, this is deep mentally, a real gem, pure psychedelic bliss. LSD feels man-made, this feels very primitive, archaic and natural.
 
9) 300ug of 1-aceteldehyde LSD makes 400g of fresh boiled thick bridgesii cactus pieces (no core, approximately 400mg mescaline) feel instead like 700mg of mescaline. I think this has to do with the possibility that 1-acetaldehyde LSD shifts the receptorome or radioligand binding of receptors "slightly away from 5-ht2a" and stronger towards the adrenal A2A, A2B, and A2C spectrum instead. This adrenal spectrum (A2A-A2C) is also the stronger dominance or habitat as well for mescaline & dmt & psilocin when compared to 5-ht2a, which is only midway on the spectrum, with the adrenal spectrum (associated with beauty & aesthetic enhancement) being more dominant with all these natural entheogens.
 
10) It is not a sacrilege to convert LSD to 1-acetaldehyde LSD cause Albert Hofmann also discovered ALD-52 at Sandoz labs. This is different from ALD-52 cause it has one extra hydrogen on the acetaldehyde adduct at the bottom indole NH group nitrogen.
 
12) LSD is more "analytical" and not as aesthetic, this feels more natural and is extremely aesthetic (beauty enhancing) like with mescaline.
 
Sample ALD-52 trip report:
 
hxxps://www.reddit.com/r/LSD/comments/4ynu/highly_underestimated_ald52/
Yes, I realize it's not technically LSD but really, it might as well be. I took 300ug thinking it would be mild if anything. Granted it wasn't as intense mentally as LSD can sometimes be, but conceptually and aesthetically it is beautiful beyond anything I ever anticipated. I feel perfect. At one. Better than I've felt in so long. I thought I could never trip again on anything but this is honestly paradigm changing for me. ALD-52 should be considered just as powerful as LSD-25 although it's a lot more relaxed and somewhat forgiving. As it is probably apparent I'm still very deep into this experience and I hope this to be an open discussion to anyone who would like to be involved.
 
My god, I just went through multiple ego death experiences beyond anything I've ever experienced from LSD before. There are no words. I mean there are plenty of "words" but none of them mean a single thing compared to any of THAT. Dear GOD. I never expected anything like this, but I sure as hell needed it. Even if I'm the only one here to express it to, as that's realistically the truth of nature anyhow. However, anyone who felt compelled to actually read through all this insanity, I just want you to know you're beautiful and you are everything. All things are right and they always will be.
 
Anyway, as far as the ALD-52, I took 300ug as I said. It was amazing and stronger than I expected, however I don't think 100ug would be very eventful to be perfectly honest. If you're concerned about it being too strong 200 might be worth it but 300 was really a great amount if you ask me. Even if you haven't taken any lysergamides before ALD-52 is rather calm compared to LSD or even mushrooms for the most part. Visually though, at least for me, it was absolutely breathtaking. Colors and textures were shifting like crazy.
 
Everything was alive and magical. Patterns were forming everywhere. I could lose myself so easily as the visuals seemed to drag my focus in without any effort. As a result, ego death was basically automatic and I reached that point multiple times. The first time I ever experienced ego death on LSD it left me with this beautiful feeling, like a deep inner glow that lasted for months afterwards. It eventually faded and I hadn't felt anything quite like it in years, but ALD-52 brought it back, and I feel like I've awakened from a spiritual coma.
 
Another thing is LSD sometimes causes my mind to wander uncontrollably unless I take my own initiative to focus, especially during the come up which can also sometimes fill me with restless confusion. Once I peak everything usually evens out, but ALD-52 put me in a state of perfect clarity from beginning to end. The come up was so smooth and comfortable.
 
I didn't notice the come down because I actually went to sleep when I felt like it was time to do so, which was an interesting surprise. Every time I've taken LSD I've had to let it run its entire course before even attempting to sleep. Often I would have to stay up for the entire day after which is obviously physically and mentally exhausting. But once I felt like the ALD-52 had made its point I went to sleep just like any other day, and woke up the next morning fully rested and mentally clear.
 
Overall, it felt very natural and I never had a single moment of uncomfortability or confusion. Just pure psychedelic bliss. I mean, I've had some amazing and extremely important experiences on LSD but honestly after the other night, think I prefer ALD-52. It felt like tripping for the first time again.
 

 

 

Random comments found on reddit to back up my dozen experiences with 1-acetaldehyde LSD (nearly identical to ALD-52) over two years:
 
1) Pandemoon said:
I dosed ALD52 like 100+ times throughout the last 4 or 5 years, in doses between 25ug and 350ug.
 
While ALD52 is very similar to LSD25, I think I can still see a slight difference. To me the visuals are different, especially the tracers. I can clearly see a difference there.
 
With 200ug+ of ALD52, when I move my hand it shows some very colorfull spirals and fractals in the tracer /smearing.
 
While with LSD25 it is just a mirroring effect that shows several of my hands. Not nearly as colorfull, just a non colored shadow (or several) of the real hand.
 
With ALD52 it's much more colorfull and intense, like painting the air with rainbow colors.
 
100ug or even 150ug don't really show a difference at all to LSD25, but with 300ug and above (my highest dose was 350ug) the differences are even more intense.
 
With 350ug I can hardly see reality anymore due to all those colorfull reflections of anything I look at.
 
I think the higher the dose the clearer the differences.
 

 

 

Quote:
 
2) ALD-52 is probably most similar to LSD relative to the other analogues (of which I have only tried ALD-52). The headspace is markedly psychedelic, it lasts 12 hours and the visuals are prominent enough. They seemed to take on a more flowing characteristic than LSD, to where I'd see objects form within the patterns.
 
3) I find it has a more mellow vibe than LSD, I'm more content to sit back and relax whereas 1p is supposedly closer to the electricity of LSD.
 
4) For what it's worth, I found the come down of ALD-52 to be better than LSD... it just felt more refreshing, like a warm hug and it tapers off gently whereas LSD is more of a sudden drop off into sobriety, but the actual peak of LSD feels more... alive to me. like my consciousness is oscillating at a super high vibration.
 
5) ALD-52 is more euphoric than LSD-25 or 1p, and I find it's also less prone to creating anxiety. Because of this, I feel like I can take much higher doses and go much deeper. I took 5 tabs and experienced absolutely no anxiety at all. I don't think I would have been able to to do the same with 25 or 1p.
 
6) Hmmm. I seem to get much more euphoria from ALD-52 over 1p. But yes, the anxiety levels are consistently low with this chemical. ALD-52 is an absolute gem.
 
7) Agree. I feel like it's a subtle power, not as forceful as 1p. But there's genuine depth to it.
I'll be the first to admit it may be placebo, but I also favor ALD-52 for this reason.
 
8] I am very fond of ALD-52 as well! For me, the headspace was very much like LSD#25; however, I felt like the former of the two had potential for a really crazy headspace. ALD-52 also had me seeing three different colors that I'd never seen in my life. I saw red-greens, orange-blues, and of course the fucking purple-yellows.
 
9) NoticesMemesOwO:
ALD is MUCH calmer than 1P in every way. 1P tends to have a shitload of anxiety on the come up and tachycardia for me and my group of friends. Its very visual but also very scary at times. especially at high doses. ALD is the best IMO. I prefer it over the real thing honestly. At high doses it was very tame, had a great visual set, and no anxiety at all. very welcoming in the way it gets you. I would pick ALD all day long, and i could take or leave 1P in all honesty.
 
10) Doubledog said:
My friends had some ALD52 blotters few years ago and described it as slightly more visual, and not so stimulating, and as upgraded version of LSD, but with just small difference.
 
11) Namaste from Shroomery (has many years experience with LSD) said:
I think you're on to something here. The 1-acetaldehyde LSD I made following your instructions dropping 3 hits or 300ug in 1 shot of sherry wine in the fridge with stirring once per hour was extremely chill. Soft around the edges. When I started coming down, it felt like 10 years of therapy.
 
I remembered good times, felt compassion. Listened to music I haven't listened to in years. Thought about friends, was at peace in a way that I haven't felt before.
 
The stars formed into animated constellations. My Bodhi statue began to juggle. I saw the Perseidies meteors not just out of the corner of my eyes but right over my face while lying in a hammock. Saw the entire movement from start to finish. They looked like giant arrows.
 
Stayed awake all day, went out to visit friends. It was very happy nostalgia. Sometimes larger doses make me totally black out. Not this time, I was awake and aware. No primal fear or paranoia.
 
Felt like I was still peaking seven hours after dropping. Sometimes I get a cracked out, confused feeling, not this time.
 
Haven't seen neon colors like that since the one and only time I was puddled.
 
Sunday's are generally filled with dread and depression for the following week. Experienced none of that. Just a long lasting afterglow. Still in a great mood now. I did get a pretty severe headache but I also drink like it's my job, and I am on a SSRI.
 
Been thinking about Ephesus and Pergamon, not sure if thats subliminal or coincidence.
 
Going to wait 3-4 months and repeat.
 
Give this a go!

 

P.S. Don't start off with that much (300ug) unless you are very advanced, start with only 1.5 hit or 150ug. 



#20 tregar

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Posted 04 January 2022 - 09:03 AM

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The end: Multiple encounters with death and depression
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This is the story of how HPBCD DMT came about: the plants taught this to me. I did not discover it. I have taken Ayahuasca over 70 times and cactus tea x 200 times. Ayahuasca seems to want to propagate herself all over the globe by any means possible, and if that means using the latest pharmacology advancements such as HPBCD, then so be it. The planet is in crisis, and Ayahuasca wants to help reverse the insane rapid destruction.
 
Daniel Pinchbeck "How Soon is Now":
The human race is careening toward extinction: rising acidity of the oceans threatens coral reefs, habitat destruction, non-native species (predatory fish, bullfrogs, fungus, pathogens), climate change (alters temperature and water levels), pollution and diseases (especially chytridiomycosis, caused from the chytrid fungus) all have been shown to contribute to worldwide amphibian declines.
 
We clear forest that are full of trees even though we continue to pump CO2 into the air even though we know it's heating up the ozone and melting ice caps; we clear forests that are full of trees that could potentially help clean that co2 out of the air, the Amazon rainforest is the lungs of the planet, but miles of it are slashed & burned every week so that cattle can graize there instead to make hamburgers, and massive soybean cultivation. We throw away plastic water bottles, and worst of all, we feed into the corporate systems that keep this destruction going.

 

 

I don't know about you, but I don't use soybeans for anything, don't eat hamburger or steaks, only fish, chicken & turkey daily, as a bodybuilder this keeps me lean daily.
 
On my 70th Ayahuasca journey using the very last of my stored away Hawaiian psychotria, she showed me a vision of my "lost 1kg container of HPBCD". I had put it away 12 years ago, as I bought it from a sports supplement supplier, once pro-hormones became illegal, I carelessly abandoned the container in a place I could care less about.
 
Ayahuasca has a long standing traditional reputation of helping people find lost personal items like rings, necklaces, etc. through visions. She once helped me find a set of important spoons that I had misplaced many years ago as well. She showed me they were buried in a drawer under forgotten clothes many years old. I once saw a vision of a beautiful woman in medieval times searching for a lost ring in her home, Ayahuasca showed me that it was at the very top of a cubbard in her kitchen.
 
All that time the HPBCD container was lost, she showed me that it was in my garage buried in a container along with plumbing parts. That night I dug it out of the container and put it in my closet for use the next day. She also showed me a vision of the mimosa tree or shrub, I put 2 and 2 together, and knew what she was telling me...to experiment with HPBCD complexed DMT, and so that is what I did. She already knew that I had experience making sublingual HPBCD pro-hormones, as I had learned it from chemist Patrick Arnold.
 
I had run out of Hawaiian psychotria, and it had been extinct for the past 3 years, perhaps diverted to all the numerous Ayahuasca centers in South America. I needed a high power alternative.
 
Daniel Pinchbeck "Breaking Open the Head" (Daniel also states in his book, that Ayahuasca is his favorite entheogen):
For many people, Ayahuasca-a slowed-down low-res interface of the DMT flash-seems to convey strong messages from the natural world, of nature as sentient energy and spirit matter, of the need to protect the planet we have been given.
 
Yage whispers that human beings are meant to be gardeners of this reality, journeyers, storytellers and singers, weavers of the sacred. DMT, on the other hand, conveys no overt human or humane message.
 
Graham Hancock, "Supernatural", pg 428:
My experience with smoked DMT was qualitatively different from the realms and beings Ayahuasca introduced me to. For whereas the Ayahuasca worlds seemed rich, luxurious, and abundant in the transformations of organic and supernatural life, DMT brought me to a world--or to some aspect of a world--that appeared from the outset to be highly artificial, constructed, inorganic, and in essence technological.
 
A little bit about me...
 
Becoming a shaman is often just as much of a curse as it is a blessing. Shamans are chosen by the Spirits at birth, but it is not until later in life (usually in their 20’s) that the shaman is struck down. The striking down of a shaman is to dismember them as a person and to have them reborn into something else.
 
The word Shaman means "to know". I am not a shaman, but have been thru alot of the near-death experiences Shaman's have gone thru, lost both my twin girls at birth, so have no children, my beloved pet Shitzu died at only age 4 from continuous bladder stones for 6 months, we did everything together...he was unable to pee so many times, we had to rush him to vet, where he was put down. He visited both of us in a dream 2 days later to tell us he was doing great in Heaven with a big smile on his face.
 
Have nearly died several times, once was hit head on by a truck when driver ran a yield sign, barely survived with numerous injuries. The hospital caught all my fractured ribs but did not diagnose my collapsed lung, so when I got home, drifted into shock in the middle of the night, wife called an ambulance and was rushed to a better hospital where they immediately diagnosed the lung condition and treated me for it.
 
Once took alot of acacia bark with Ayahuasca instead of the normal Hawaiian psychotria I use, and went into a serious serotonin syndrome shock, for an hour and a half I sweated my ass off sitting in the bathtub, I told my wife goodbye while my dog watched in a sad state...by some miracle pulled out of it, believe it was the high levels of maoi's in the acacia that interacted with the rima's in the Ayahuasca, bad combination. My forehead was pouring sweat for 1.5 hours, was in severe shock and trembling, and knew I was gonna die.
 
Lost everything in a 100 year severe flood, my home and all my belongings, had just gotten married to my beautiful wife and all the newlywed gifts perished...right after that we moved to an apartment complex, and 5 months later all our belongings again perished as they burnt to the ground after a disgruntled teen threw a lit blunt into the apartment complex after his girlfriend dumped him.
 
Had it not been for the policeman banging on the door of the apartment, we would have surely burned in the flames, as we were on the 3rd floor & asleep as I worked 2nd shift at the time. We ran down the steps in only our bare feet and suffered smoke inhalation.
 
Have been thru some near-death experiences similar to a Shaman, who lives on the outskirts of society. Lifting weights, walking in nature with my dog, going to the waterpark with a season pass every summer, and reading Bible all keep my spirits up.
 
Some of you have contacted me via messenger to let me know that you would like to experience this for other reasons than the visions, to help with treating depression. I will tell you this, yes, Ayahuasca can help to cure not only anger issues, melancholy, drug abuse & addictions, but also depression. She is also able to grow brand new neurons in the brain every time a journey is taken, she has cured people of all sorts of afflictions and ailments, even severe depression. I feel an afterglow for a couple days after a journey, and this refreshed serotonin reset often lasts for a couple weeks.
 
Celebrities who have battled major depression: Dwayne Johnson "the Rock", Katy Perry, Jon Hamm, Lady Gaga, Michael Phelps, Kristen Bell, Bruce Springsteen, Gwyneth Paltrow, Ashley Judd, Naomi Judd, Ryan Phillippe, J.K. Rowling, Sheryl Crow, Terry Bradshaw, Buzz Aldrin, Tipper Gore, Wayne Brady, Jim Carrey, Robin Williams, Brittany Murphy.





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