Paradox
©
Fisana

Jump to content


Photo
- - - - -

crystal Psilocybin

crystal psilocybin

  • Please log in to reply
10 replies to this topic

#1 kingfreddys

kingfreddys

    Mycotopiate

  • Expired Member
  • 245 posts

Posted 23 January 2009 - 07:16 PM

let's say swim extracted and purified psilocybin into crystal form. Would this crystal be a suitable solute to form a psilocybin/H2O solution? SWIM wants to experiment in the lab and develop the by far most convenient and pleasant ingestion method possible.(although chocolates are dank) Does SWIY perhaps know how to determine the shelf life of such a solution?

#2 EmmisonJ

EmmisonJ

    halcyon & on & on

  • Free Member
  • 959 posts

Posted 23 January 2009 - 07:51 PM

do you mind listing the full details of the extraction procedure? i'm not aware of a psilocybin extract to give crystals, just psilocin.

my knowledge and reading in the chemistry behind this is very limited, less than very limited actually. but psilocybin and psilocin both in their natural form are soluble in water, as would be most salt forms just to different extents depending on the salt. but if you have the crystal and it's pure enough then it would dose close to erowid's psilocybin chart for synthetic psilocybin, but of course that would depend on what form it's in as well. either way, any type of pure psilocybin or psilocin is going to dose very low in any pure form, easily fitting into a small gelcap even. no need for the water except to wash the gelcap down with.

not many people have experimented with storage of crystalized psilocybin although it is more stable than psilocin. you'd be a pioneer in testing this as far as i know. but one things for sure, best storage for it is with desiccant in an airtight container in the freezer with something blocking light from it. psilocybin should store well but it might be difficult to find people to attest to that first hand as most people just eat their booms without an advanced extraction as psilocybin/psilocin are supposedly notoriously difficult to extract.

so what tek/procedure are you referring to??


http://www.thenook.o...showtopic=29296

for those of you who don't have access:

The following method described shows an easy method to isolate pure psilocin from fungus in less than 4 hours. If a more pure product is wanted, the fairly pure psilocin can be recrystallized to produce large pure crystals.
20 grams of dried fungus is powdered in a coffee grinder to a fine powder. This is added to a glass container (~500 ml) along with 200 ml of distilled water and 40 ml distilled white vinegar (5% acidity). ~200 mg of vitamin C was also added to keep the psilocin from decomposing. This mixture was allowed to stir at room temperature for 1 hour and then the container was placed in a bath of boiling water to heat the mixture to 70 degrees C. After the mixture reached this temperature, it is filtered through multiple coffee filters (3-4 is good) and the filtered (be sure to squeeze out all the juice!) liquid is set into a cold water bath to cool it down. The extracted fungus is recovered and put into another container along with 150 ml water and 20 ml vinegar. This is again heated to 70 degrees C and then filtered as before. The filtrate is again cooled down and then added to the 1st extraction. The combined filtrates should give somewhere around 300 ml of liquid. Add about 30 ml of chloroform (xylene should also work, as psilocin is solubile in this as well) and begin stirring gently (you don't want emulsions, do you?). While stirring, SLOWLY add NaOH solution (~10 % NaOH is fine). I would suggest a drop by drop addition, as the pH can raise raphidly after a certain point. Target pH is 8, just try not to go over pH 9, as the alkaloids can decompose pretty fast at high pH. After the pH is at 8-9, continue to stir gently for about 20 minutes (electric stirrers are nice) and the psilocin will migrate into the chloroform (or xylene) layer. This is poured into a separatory funnel (or something similar) and the bottom chloroform layer is removed and set aside. The water layer is again stirred and 15 ml of chloroform is added for a second extraction. After 20 minutes of stirring, this is again separated in a separatory funnel and the chloroform recovered. These two chloroform extracts are combined and put into a small beaker. To this beaker, anhydrous MgSO4 is added (just oven dry epson salts in an oven at 450 degrees F for about an hour) to absorb any water. Usually only a gram or so is needed. Stir the chloroform with the MgSO4 for a minute or so and then filter through a "good quality" filter paper so you catch all the fine particles. The resulting chloroform layer will have a light yellow color. Now you have two choices:
You can evap the chloroform quickly to yield a fairly pure psilocin powder, or let it evaporate slowly to get larger and more pure crystals. Recrystallization can be carried out with methanol or a 3:1 heptane:chloroform. The recrystallized material is very pure and 20 mg is equivelent to 4-5 grams of mushrooms. Average yield for this method is about 60 mg of pure crystals (after recrystallization). The crystals do decompose at room temperature over time. The yellow crystals turn green in about a week or so if left out. To preserve the psilocin, put ~50 mg of psilocin in a small container and add ~50 mg ascorbic acid and 20 ml water. The psilocin will dissolve, but it does so slowly. You now have a solution with 2.5 mg psilocin per ml. This can be stored for many months in the refrigerator (possibly longer). An interesting note is that this "psilocin water" can be evaporated to give white needle crystals which don't seem to degrade at room temperature. Perhaps this is the way to stabilization!

Attached Files



#3 kingfreddys

kingfreddys

    Mycotopiate

  • Expired Member
  • 245 posts

Posted 24 January 2009 - 06:17 PM

pardon my inaccuracy. in this process the psilocybin is converted into psilocin, what is left is a very very pure psilocin.

found at rhodium:

A representative sample of 2 to 10g of dried mushrooms is ground to a fine powder by mortar and pestle. The powder is mixed with 100 mL of dilute acetic acid in a 250-mL beaker. The pH is readjusted to pH 4 with glacial acetic acid. After standing 1 h, the beaker is placed in a boiling water bath for 8 to 10 min or until the internal temperature of the acid mixture reaches 70°C. The beaker is removed and cooled to room temperature under running water. The acid mixture is separated from the mushroom powder by suction filtration using glass wool. The filtrate is brought to pH 8 with concentrated ammonium hydroxide and quickly extracted with two 50-mL portions of diethyl ether. Gentle mixing instead of shaking should be used to prevent an emulsion. The ether is dried over sodium sulfate, filtered, and evaporated under nitrogen with no applied heat.

Crude psilocin will appear as a greenish residue. Recrystallization from chloroform/heptane (1:3) yields white crystals. The resulting powder can then be submitted to infrared and mass spectral analyses



#4 Shadowlord

Shadowlord

    Shadowmancer.

  • Editorial Moderator
  • 3,676 posts

Donator

Posted 24 January 2009 - 11:11 PM

I had planned on 'noccing up some jars and doing some cultivating as it is but this thread only increases my interest and desire.
I have enjoyed extracting Mescaline from Cacti and would love to attempt to extract Psilocin.
Has anyone here had the opportunity to sample Psilocin? Is there a quantitative difference to the experience vs. Ingesting 'Shrooms normally.
I have a lot more experience w/ Mesc and/or LSD than I have w/ 'Shrooms.
And only tripped 2x out of maybe 8 attempts w/ 'Shrooms thus far.
Great thread K.F. and thanks for the link/info E.J. Great stuff as always.:thumbup:

#5 lysergic

lysergic

    Down on the Pharm

  • Expired Member
  • 2,431 posts

Posted 25 January 2009 - 12:50 AM

I'd love to have a soxhlet for things like this :teeth:

#6 EmmisonJ

EmmisonJ

    halcyon & on & on

  • Free Member
  • 959 posts

Posted 25 January 2009 - 03:43 AM

I had planned on 'noccing up some jars and doing some cultivating as it is but this thread only increases my interest and desire.
I have enjoyed extracting Mescaline from Cacti and would love to attempt to extract Psilocin.
Has anyone here had the opportunity to sample Psilocin? Is there a quantitative difference to the experience vs. Ingesting 'Shrooms normally.
I have a lot more experience w/ Mesc and/or LSD than I have w/ 'Shrooms.
And only tripped 2x out of maybe 8 attempts w/ 'Shrooms thus far.
Great thread K.F. and thanks for the link/info E.J. Great stuff as always.:thumbup:


no prob man, the trip of the crystallized psilocin is indeed different than a mushroom trip in the sense that a mescaline experience is different from an entire cacti experience. from the few trip reports i've read (only 3) from ingesting psilocin in this method was a great success and dosed low close to erowid's chart which showed it must have had some decent purity. both trip reports were a bad trip, said it was a very dark and paranoid trip and the conclusion is that some of the other, lesser, alkaloids in the mushroom really play a larger role on influencing the trip than previously though. this is probably only a procedure fit for the hard-headed. swim is hard headed with lsd, mescaline, dob, 2ci, but for whatever reason even though swim has shroomed for years (and even uber-high doses) swim is a light-weight with shrooms, the reason why swim is so sensitive to them is because mushrooms are so "gray area", confusing and mysterious, swim never know quite what to make of it. mescaline and lsd just seem so much more profound, whereas mushrooms are more like you're in a eery funhouse with no guide. so swim has never considered doing this process himself unless he were to just give it to a hard-headed friend which he might do someday

no doubt it was their mindset going into it, the thought of being a pioneer with this can make you very paranoid about every little sensation, unsure of your product, which is probably exactly what led to the bad trips. plus he was a pioneer with the dosing too, unsure of exact purity means unsurity of dosing. for example recrystallized mescaline you may only need 400mlg, but bad sanchez you may need a gram. sounds like he may have taken more than he was prepared for as this was a "test lauch". also the 2nd trip has a definite trigger for the bad trip with the phone, always turn away clocks and unplug/turn off phones, pull blinds down and do not answer the door! both trip reports were by the same guy, triptamine. but he's obviously a very knowledable person, no first timer and his trip reports are kinda scary. perhaps dosed too high, psychedelics are unpredictable so it's hard to say but here are his trip reports:
1. http://www.thenook.o...765&hl=psilocin
2. http://www.thenook.o...541&hl=psilocin

Today was set to be the day to try some of my recently extracted and recrystallized psilocin. The crude psilocin was dissolved in heptane:chloroform (3:1 â€" 7 ml total volume). I found it difficult to dissolve, but it slowly went into solution. I slowly evaporated this under N2 until ~3 ml volume remained and poured remaining liquid into another vial. The crystals were dried under N2 and collected and weighed to be 28 mg. 21 mg. Of this was dissolved in ~10 ml distilled water with ~50 mg ascorbic acid to preserve the psilocin. The psilocin crystals were slightly soluble and much remained undissolved on the bottom of the vial. This was placed in the refrigerator (~38 F) until today. The remaining 7 mg was put in the freezer dry and under N2.

The trip beings:

21 mg psilocin in solution (most of the psilocin had dissolved by this time) was put into my mouth and held there for about 5 minutes at 5:30 PM. The taste was bitter, but easily bearable. I then swallowed the liquid. I proceeded to take a shower and was already feeling some effects at about 5-10 minutes into it. Overall, I was in fairly good spirits, but was slightly upset about the trip being postponed (I thought it would be moved to another day). I was also fairly tired from work today and in retrospect, I probably should have waited until I was more rested.

Anyhow, after the shower, I went into the living room and put on some music. Sting's “brand new day” was already in the CD player, so playing was easy! As the trip built intensity, I kept trying to focus on visuals, but I was continually distracted by thoughts of work. Basically, I tend to think of work even after I have had enough. Hard to turn off the mind, I guess! At about the 1-hour point (6:30 PM) I decided that the trip was about the intensity of a 2-3 gram trip, but I wanted a bit more. After contemplating taking the 7 mg in the freezer, I decided that it would be a good idea. Again, in retrospect, it is probably better to stick with the planned experiment instead of changing it while it is in progress.

So, the music plays on and on, and my mind gets thinking…basically, I entered a paranoid mindset (which has happened once before in my 007 trip) in which I thought there was a chance that the authorities that be knew what I was up to. When tripping, this is not a good thing to get into your mind, as your imagination is usually quite good on mushrooms (or psilocin â€" whatever). My paranoia started to get a little out of hand, so I stopped the music and went to the bedroom with my wife and newborn daughter. I tried to still my thoughts, but the paranoia was still there. Finally, after a few minutes (which seemed like hours) the paranoia was gone, but it was replaced by a strange sensation: the loss of sensation! I started to feel faint and could feel strong tingling in all my limbs. As I lay, the feelings were getting stronger and stronger and I was very concerned that something was going wrong. I held my wife close, which comforted me some, but the tingling and light-headedness increased.

I was scared that I may have taken too much psilocin and was poisoning myself. I felt like if I were to wait 10 more minutes, I would be passed out, or worse â€" dead! I remembered reading somewhere that activated charcoal can be used to soak up alkaloids in the stomach (probably none there by now, but…) and can even remove them from your bloodstream. I was definitely up for the test!!! I got a small jar of charcoal and added water. It fizzed and I was a little concerned about putting this in my mouth, but considering the circumstances, I decided it was best to proceed. I touched my tongue onto the wet charcoal and swallowed. I repeated this 3-4 times to ingest about 1 tablespoon of charcoal. I felt some relief almost immediately (probably from just focusing on the task at hand), but all was not over yet. The dizziness came and went over the next hour and a half and was accompanied by feelings of being quite scared. I thought that I was literally fighting for my life. Whether this is true or not, I will never know. I fought with all my might to stay conscious. At about 8 PM, I chose to vomit (as I was fairly nauseous and thought it might expel some of the toxins). During my toilet-filling episode, I thought I was going to die and I asked God to help me. With each spew, I felt better and I got the message that Jesus had saved me. I thanked Jesus for sparing my life and got back into bed. An interesting note was that none of the charcoal came out. Perhaps it is very dense after absorbing so many alkaloids! Anyway, after purging, I felt far better (but still not completely ok). I then swore off doing any more extractions of any kind. Natural is ok, but purification can be very dangerous!

I initially said I was also done with the mushroom, but then came to my senses and changed my mind. I will probably take a good long break though. I have decided to get rid of my drugs, as it is not worth the paranoia. Especially when considering our 1st newborn daughter in this equation. After sobering up somewhat, I placed my hand on my daughter's belly. She was sleeping, but responded with every movement and emotion. I felt truly connected with my daughter. She was incredibly responsive during this time and would wave her hands out and stuff. It was so cool and made me very glad to be alive. I do love life, but sometimes I need a good psychedelic kick in the rear to help me remember. I now remember: the answer is love.

Triptamine



trip report # 2

So, last December 21 mg of psilocin was taken which seemed (at about the 2 hour point) to be similar to about a 2-3 gram mushroom trip. This was boosted with an additional 7 mg, which, in retrospect was a bad idea. A paranoid mind state had provided feelings of loosing consciousness and fear of death. Since then, lesser doses of 10, 16, 21 and more recently 22 mg were taken. The lower doses provided good trips, although something was lacking. Visuals were not very strong, even though the trip did seem intense at points. Perhaps by using pure psilocin, some of the "magic" is lost. Anyway, now trying a slightly higher level of 22 mg, and listening to some relaxing music (enya, erasure, pink floyd, et. al.) to set the mood.

Everything was going well in the beginning. In fact, at the 2 hour point, walking outside seemed like a good idea, but the wind and rain suggested that it was not yet time. Around this time, it seemed like about 2.5-3 grams of fungus material. Then the phone rang. The answering machine picked up, but the message was heard. The message was one which was filled with guilt inducing material and was one which was from someone who is old, loved, and respected. Starting to feel bad, a mind state of guilt developed and to make a long story short, the thoughts in the mind caused a feeling of lightheadedness and as if close to loosing consciousness. Feelings that the world and all that happened in it was resting on us was difficult to bear and created more lightheadedness. Very close to loosing consciousness and very afraid of death, someone tried to reason that it does not all rest on us. It is the responsibility of others to take care of themselves and visa-versa. This helped somewhat, but the mind was already carrying on in a negative direction.

After a short while longer, activated charcoal (~1 Tsp) was taken to try to absorb some of the psilocin. This does seem to be effective, by the way, as this trip was substantially over in ~3 hours. After about 5 minutes, purging was successfully attempted with little of the charcoal exiting. Perhaps it is too dense to come out, I don't know. Purging helped some, but for the next hour, a struggle to maintain conscious and clinging on to life was a continuous battle. Only the love of my wife and child gave hope. Finally, at about the 3 hour point, and feeling substantially better, but still shakey, drugs were sworn off. No more! Mainly, the purified chemicals, which seem to not only have the "magic" removed, but also seem to be more dangerous. After perhaps a hundred mushroom trips and no reactions like this, one can only think that there is something not right about taking the purified compound. Psilocin, when pure, does not have much anxiety on the come up, which seems desirable, but also it lacks the wonder and amazement of the mushroom experience. It may be unlikely, but perhaps psilocin has a different effect than psilocybin. Certainly more likely, is that the combination of psilocin, psilocybin, beocystin and other alkaloids are needed to provide the rich experience many know.

The psychedelic experience is a very sacred thing, but somehow it has been tainted by trying to purify it. Perhaps it is best as nature made it. Perhaps we should leave it that way, or perhaps we just need to investigate it more carefully.

Tripping is still something very special and further experiments in hyperspace will likely occur, but a good break is now needed to integrate these experiences into life.

Triptamine



#7 cheech

cheech

    wizard of sorts

  • Free Member
  • 569 posts

Posted 25 January 2009 - 12:34 PM

i remember hearing that when maria sabina sampled synthetic psilocybin she said the magic was there.

#8 weeeeeee

weeeeeee

    humanoid

  • Expired Member
  • 1,857 posts

Posted 25 January 2009 - 01:33 PM

damn sounds intense

#9 Shadowlord

Shadowlord

    Shadowmancer.

  • Editorial Moderator
  • 3,676 posts

Donator

Posted 25 January 2009 - 02:28 PM

Well, It would have been a while b/4 I was ready to attempt such an extraction but I think I will wait until I have much more experience w/ 'Shrooms b/4 ever attempting something like this.
I have little or no problems w/ LSD or Mesc but have had poor results w/ 'Shroom thus far. Hence the interest in extractions.
I don't know if it is because I don't get the fungus broken up enough. (I've eaten them fresh and dried, but chew only enough to wash them down w/ liquid ) but out of 8-10 attempts I have only tripped good 2 times w/ 6 dud efforts and several attempts that left me feeling cold, sad and depressed. All in a way that made me glad that Shrooms don't last as long as L or M and leaves me disappointed as so many have had such excellent results w/ Magic Fungi.
The 8-10 attempts are over 20yrs, so I have never had the chance to truly experiment w/Fungi. Thus, I am not ready to throw the towel in just yet. I plan on making a tea from them next time and see how that works. I also will weigh out my dosage next time as I always just ate the bag ( 1/8) or whatever.
Still an interesting extraction, but triptamines' experiences have tempered my enthusiasm a little. Purifying Mescaline works so well, I was thinking doing the same here might be helpful.
Ironic, at a 'Shroom cultivation site that Mycology is my weakest point :lol:

#10 Rhyno

Rhyno

    DEATH TO POACHERS!

  • VIP
  • 982 posts

Posted 25 January 2009 - 03:26 PM

That is why we are all here Shadow. You are a super quick study so soon you won't feel that way.

#11 greenmeanie

greenmeanie

    Mycophiliac

  • Free Member
  • 233 posts

Posted 26 January 2009 - 02:48 AM

If one were to isolate pure Psilocin crystals, they would keep best in the solid form, sealed away from water light and air. H2O or ethanol (magic laudanum!) solution would be one method of ingestion, but don't store it that way for any length of time.




Like Mycotopia? Become a member today!